Efficacy and safety of moxidectin, synriam, synriam-praziquantel versus praziquantel against schistosoma haematobium and S. mansoni infections: a randomized, exploratory phase 2 trial [PDF]
Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or clinical ...
Puchkov, Maxim +23 more
core +2 more sources
Is arachidonic acid an endoschistosomicide?
Schistosoma mansoni and Schistosoma haematobium are intravascular, parasitic flatworms that infect >250 million people in 70 developing countries, yet not all people of the same community and household are afflicted.
Violette Said Hanna +4 more
doaj +1 more source
Cytokine responses to
Background The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium ...
Mduluza Takafira +17 more
core +2 more sources
Schistosoma haematobiumInfection and Buruli Ulcer [PDF]
No abstract available.
Scott, Janet T. +7 more
openaire +4 more sources
Evaluation of the health-related quality of life of children in Schistosoma haematobium-endemic communities in Kenya: a cross-sectional study. [PDF]
BACKGROUND: Schistosomiasis remains a global public health challenge, with 93% of the ~237 million infections occurring in sub-Saharan Africa. Though rarely fatal, its recurring nature makes it a lifetime disorder with significant chronic health burdens.
Charles H. King (78462) +44 more
core +1 more source
Prevalence of S. haematobium in persistent hot-spot and low-prevalence shehias Table 1 shows the prevalence of S. haematobium in children visiting the primary schools located in any of the seven study shehias, stratified by survey year. The average S. haematobium prevalence across all three survey years in 9 – 12 years old schoolchildren was 20.0 % (95
Pennance, Tom +9 more
openaire +2 more sources
Population Genetic Structure and Hybridization of Schistosoma haematobium in Nigeria
Background: Schistosomiasis is a major poverty-related disease caused by dioecious parasitic flatworms of the genus Schistosoma with a health impact on both humans and animals.
Amos Mathias Onyekwere +6 more
doaj +1 more source
Background Schistosomiasis is still a public health issue in certain areas of developing countries (especially in sub-saharan Africa). Schistosoma haematobium is a proven carcinogenic agent that causes mainly bladder squamous cell carcinoma. This type of
Boubacar Efared +6 more
doaj +1 more source
Toward measuring Schistosoma response to praziquantel treatment with appropriate descriptors of egg excretion [PDF]
The control of schistosomiasis emphasizes preventive chemotherapy with praziquantel, which aims at decreasing infection intensity and thus morbidity in individuals, as well as transmission in communities.
Xiao-Nong Zhou (92570) +70 more
core +2 more sources
Whole-genome sequence of Schistosoma haematobium [PDF]
Schistosomiasis is a neglected tropical disease caused by blood flukes (genus Schistosoma; schistosomes) and affecting 200 million people worldwide. No vaccines are available, and treatment relies on one drug, praziquantel. Schistosoma haematobium has come into the spotlight as a major cause of urogenital disease, as an agent linked to bladder cancer ...
Young, Neil D. +27 more
openaire +5 more sources

