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The Schistosoma Granuloma: Friend or Foe? [PDF]

open access: yesFrontiers in Immunology, 2013
Infection of man with Schistosoma species of trematode parasite causes marked chronic morbidity. Individuals that become infected with Schistosomes may develop a spectrum of pathology ranging from mild cercarial dermatitis to severe tissue inflammation, in particular within the liver and intestines, which can lead to life threatening hepatosplenomegaly.
Gabriella Aviello   +2 more
exaly   +6 more sources

Life stage-specific glycosylation of extracellular vesicles from Schistosoma mansoni schistosomula and adult worms drives differential interaction with C-type lectin receptors DC-SIGN and MGL

open access: yesFrontiers in Molecular Biosciences, 2023
Schistosomes can survive in mammalian hosts for many years, and this is facilitated by released parasite products that modulate the host’s immune system.
Marije E. Kuipers   +9 more
doaj   +1 more source

Focal eosinophilic infiltration of the liver, benign or malignant?

open access: yesClinical Case Reports, 2021
Focal eosinophilic infiltration (FEI) of the liver shares imaging characteristics with malignant hepatic lesions but should be suspected when concomitantly observing eosinophilia. While in itself benign, the cause of FEI should be sought and treated.
Wouter Claeys   +7 more
doaj   +1 more source

A novel, non-neuronal acetylcholinesterase of schistosome parasites is essential for definitive host infection

open access: yesFrontiers in Immunology, 2023
Schistosomes are long-lived parasitic worms that infect >200 million people globally. The intravascular life stages are known to display acetylcholinesterase (AChE) activity internally as well as, somewhat surprisingly, on external tegumental ...
Patrick J. Skelly, Akram A. Da’dara
doaj   +1 more source

Functional Annotation of Some Hypothetical Genes in the Schistosoma Parasite Based on Reciprocal Best Structural-hit Relationship [PDF]

open access: yesResearch in Molecular Medicine, 2022
Background: The Schistosoma parasite is responsible for several overlooked tropical diseases, which cause significant economic losses in livestock. This parasite is increasingly found in the central areas of the northern provinces of Iran. To generate an
Arezou Askari Rad   +3 more
doaj  

Schistosome Vaccine Adjuvants in Preclinical and Clinical Research

open access: yesVaccines, 2014
There is currently no vaccine available for human use for any parasitic infections, including the helminth disease, schistosomiasis. Despite many researchers working towards this goal, one of the focuses has been on identifying new antigenic targets. The
Rachel Stephenson   +3 more
doaj   +1 more source

The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis

open access: yesVirulence, 2020
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years.
Catherine S. Nation   +2 more
doaj   +1 more source

Study on Prevalence of Parasitic Infections Among Hepatitis C Virus Patients in Egypt [PDF]

open access: yesArchives of Razi Institute
Introduction: Hepatitis C virus (HCV) is a viral infection affecting 71 million people worldwide. A high prevalence of co-infection has been observed with parasitic infections, such as Schistosoma mansoni, Fasciola sp., and Toxoplasma gondii, all of ...
Maryam Garas   +4 more
doaj   +1 more source

Booming Omics in Schistosoma [PDF]

open access: yesTrends in Parasitology, 2021
Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al. and Wang et al. deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite ...
Le Govic, Yohann   +2 more
openaire   +3 more sources

Atypical Presentation of Urinary Schistosomiasis

open access: yesJournal of Microbiology and Infectious Diseases, 2019
Schistosomiasis or Bilharziasis is a water-borne parasitic disease which affects different organs depending on species involved. Urinary schistosomiasis is diagnosed mainly by the presence of urinary complaints, urinary excretion of parasite eggs and ...
Sunayana Mukesh Jangla   +3 more
doaj   +1 more source

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