Results 61 to 70 of about 7,299 (159)

Performance characteristics of diagnostic assays for schistosomiasis in Ontario, Canada

Therapeutic Advances in Infectious Disease, 2023
Introduction: Due to lower intensity of infection and greater intervals from last exposure, parasitologic detection methods for schistosomiasis are poorly sensitive in non-endemic areas, challenging accurate diagnosis. Methods: We evaluated parasitologic
Rachel Lau, Leila Makhani, Osaru Omoruna, Celine Lecce, Eric Shao, Marlou Cunanan, Filip Ralevski, Karamjit Cheema, Andrea K. Boggild   +8 more
doaj   +1 more source

Pharmacological Inhibition of c‐Jun N‐Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler, Lukas Knedla, Maximilian Hagen, Verena von Bülow, Heike Müller, Annette Tschuschner, Daniel Zahner, Simone Haeberlein, Max F. Moescheid, Anita Windhorst, Monika Burg‐Roderfeld, Dieter Glebe, Bernardo Pereira Moreira, Céline Lesieur, Andreas Schmid, Franco H. Falcone, Christoph G. Grevelding, Elke Roeb, Martin Roderfeld   +18 more
wiley   +1 more source

Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra‐Pubic Mass: A Case Report

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Rawa Badri, Safa Abdalrhim, Aymen Hamid, Ahmed Salah Aldeen, Ahmed Tahir, Mohamad Osama Ahmad   +5 more
wiley   +1 more source

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Lung Involvement in Chronic Schistosomiasis with Bladder Squamous Cell Carcinoma

Emerging Infectious Diseases, 2018
We report a case of chronic Schistosoma haematobium infection with pseudometastatic pulmonary nodules and high-grade squamous cell carcinoma in a 30-year-old man in Mali. Lung biopsies revealed chronic pulmonary involvement of S.
Anastasia Saade, Edith Carton, Audrey Mansuet-Lupo, Romain Jouffroy, Diane Damotte, Hélène Yera, Marie-Pierre Revel, François Goldwasser   +7 more
doaj   +1 more source

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, Volume 101, Issue 4, Page 833-845, July/August 2025.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Co‐endemicity of schistosomiasis and tegumentary leishmaniasis: Spatial co‐clustering in endemic areas

Tropical Medicine &International Health, Volume 30, Issue 6, Page 556-568, June 2025.
Abstract Objectives Schistosomiasis and tegumentary leishmaniasis simultaneously affect areas in tropical and subtropical regions. Co‐infected individuals show a less‐than‐optimal response to treatment and increased regulatory immune responses. However, no study has determined where Schistosoma–Leishmania co‐infections are more likely to occur ...
Genil Mororó Araújo Camelo, Jeferson Kelvin Alves de Oliveira Silva, Dharliton Soares Gomes, Laura Maggi, Stefan Michael Geiger, David Soeiro Barbosa, Deborah Aparecida Negrão‐Corrêa   +6 more
wiley   +1 more source

Rectal Polyp Caused by Schistosoma Haematobium

Journal of Gastrointestinal and Liver Diseases, 2014
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Nick, Janssen, Jeroen, Heemskerk, Arjan P, Willig, Susan M, Toebosch   +3 more
openaire   +3 more sources

Schistosomiasis haematobium prevalence among haematuric patients: Parasitological and immuno-assay

Beni-Suef University Journal of Basic and Applied Sciences, 2017
Schistosoma haematobium infection is a clinically important water born parasitic disease. This study was conducted to detect the prevalence of schistosomiasis haematobium among haematuric patients by microscopy and immunoassay.
Marwa A. Ghieth, Amr M. Lotfy
doaj   +1 more source