Results 91 to 100 of about 64,179 (295)

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

open access: yesPLoS Neglected Tropical Diseases, 2022
Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not.
Jia Shen   +6 more
doaj   +1 more source

An improved genome assembly of the fluke Schistosoma japonicum

open access: yesPLoS Neglected Tropical Diseases, 2019
Background Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China and the Philippines. A single draft genome was available for S. japonicum, yet this assembly is very fragmented
F. Luo   +14 more
semanticscholar   +1 more source

Tubulin Polymerization Promoting Proteins: Functional Diversity With Implications in Neurological Disorders

open access: yesJournal of Neuroscience Research, Volume 103, Issue 5, May 2025.
A family of human proteins, encoded by Tubulin Polymerization Promoting Proteins (TPPP), is highly conserved across species. TPPP displays remarkable functional diversity and is implicated in various neurological disorders. Image created with BioRender.com.
Paloma J. Diaz   +3 more
wiley   +1 more source

Patent Landscape of Helminth Vaccines and Related Technologies [PDF]

open access: yes, 2013
Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths.
Burke, Rayna   +4 more
core   +1 more source

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]

open access: yes, 2019
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing   +5 more
core   +2 more sources

Asian Schistosomiasis: Current Status and Prospects for Control Leading to Elimination

open access: yesTropical Medicine and Infectious Disease, 2019
Schistosomiasis is an infectious disease caused by helminth parasites of the genus Schistosoma. Worldwide, an estimated 250 million people are infected with these parasites with the majority of cases occurring in sub-Saharan Africa.
Catherine A. Gordon   +8 more
doaj   +1 more source

Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets. [PDF]

open access: yesPLoS Computational Biology, 2014
Blood fluke proteases play pivotal roles in the processes of invasion, nutrition acquisition, immune evasion, and other host-parasite interactions. Hundreds of genes encoding putative proteases have been identified in the recently published schistosome ...
Shuai Liu   +7 more
doaj   +1 more source

Schistosoma japonicum-Associated Colorectal Cancer: A Review.

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2019
Schistosoma japonicum is a digenetic blood fluke that has been implicated in the carcinogenesis of several human malignancies, notably liver and colorectal cancer (CRC). Schistosoma japonicum-associated colorectal cancer (SACC) is a distinct subtype with
H. Hamid
semanticscholar   +1 more source

Development of a novel real-time polymerase chain reaction assay for the sensitive detection of Schistosoma japonicum in human stool.

open access: yesPLoS Neglected Tropical Diseases, 2021
BackgroundElimination and control of Schistosoma japonicum, the most virulent of the schistosomiasis-causing blood flukes, requires the development of sensitive and specific diagnostic tools capable of providing an accurate measurement of the infection ...
Sara Halili   +4 more
doaj   +1 more source

In Vitro Effects of Vanadate Erbium/Silver Oxide (ErVO4/AgO) and Vanadate Iron/Silver Oxide (FeVO4/AgO) Nanoparticles on the Adult of Fasciola hepatica

open access: yesVeterinary Medicine and Science, Volume 11, Issue 3, May 2025.
ABSTRACT Fascioliasis is a common hepatic parasitic disease that is caused by Fasciola, resulting in significant economic losses by reducing production and consigning viscera in animals. Currently, there is little research regarding the impact of chemical compounds on the ultrastructure and motility of adult F. hepatica.
Arbabi Mohsen   +5 more
wiley   +1 more source

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