NOD-like receptor protein 3 (NLRP3) inflammasome was reported as expressed in schistosomiasis-induced liver fibrosis (SSLF). We used an NLRP3 inflammasome inhibitor, MCC950, to investigate whether it inhibited liver fibrosis, and explored the preliminary
Wen-juan Zhang, Z. Fang, Wen-qi Liu
semanticscholar +1 more source
Schistosomiasis is a debilitating parasitic disease caused by platyhelminthes of the genus Schistosoma, notably Schistosoma mansoni, Schistosoma haematobium, and Schistosoma japonicum. Pioneer researchers used radiation-attenuated (RA) schistosome larvae
Rashika El Ridi, Hatem Tallima
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Les Précipitines sériques dans les Bilharzioses humaines et expérimentales à Schistosoma mansoni, S. haematobium et S japonicum [PDF]
A Caprón+5 more
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BackgroundChemotherapy for schistosomiasis has been around for 100 years. During the past century, great efforts have been made to develop new antischistosomal drugs from antimonials to nonantimonials, and some of these have been used extensively in ...
S. Xiao, Jun Sun, Ming-gang Chen
semanticscholar +1 more source
Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum
The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described.
Chuan-Xin Yu+7 more
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Five-year impact of repeated praziquantel treatment on subclinical morbidity due to Schistosoma japonicum in China [PDF]
We report the 5-year impact (1996-2001) of repeated praziquantel chemotherapy on subclinical morbidity related to Schistosoma japonicum infection. We repeated stool examinations and hepatosplenic ultrasonography in a cohort of 120 individuals living on ...
Dessein, A.+6 more
core
Granulocyte-macrophage colony-stimulating factor enhances the production of eosinophil chemotactic lymphokine by egg-associated granulomas of Schistosoma japonicum-infected mice [PDF]
Makoto Owhashi+2 more
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Colon polyps with or without Schistosoma japonicum
Schistosoma japonicum, which has been endemic for a long time, associated colon abnormality has also been sporadically reported. The majority of patients with Schistosomiasis japonicum infected may mainly presented as acute manifestation or become chronic complication, known as schistosomiasis liver change, intestinal tract lesions and other system ...
Youhong, Cao, Chen, Yuan
openaire +2 more sources
Granulocyte-macrophage colony-stimulating factor produced by splenic T lymphocytes of mice infected with Schistosoma japonicum [PDF]
Makoto Owhashi, Yukifumi Nawa
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Inhibition of immediate and Arthus responses to schistosome egg antigens by T cells from Schistosoma japonicum-infected mice [PDF]
Abram B. Stavitsky, G R Olds
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