Results 151 to 160 of about 64,179 (295)

NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-κB

open access: yesParasites & Vectors, 2019
NOD-like receptor protein 3 (NLRP3) inflammasome was reported as expressed in schistosomiasis-induced liver fibrosis (SSLF). We used an NLRP3 inflammasome inhibitor, MCC950, to investigate whether it inhibited liver fibrosis, and explored the preliminary
Wen-juan Zhang, Z. Fang, Wen-qi Liu
semanticscholar   +1 more source

Why the radiation-attenuated cercarial immunization studies failed to guide the road for an effective schistosomiasis vaccine: A review

open access: yesJournal of Advanced Research, 2015
Schistosomiasis is a debilitating parasitic disease caused by platyhelminthes of the genus Schistosoma, notably Schistosoma mansoni, Schistosoma haematobium, and Schistosoma japonicum. Pioneer researchers used radiation-attenuated (RA) schistosome larvae
Rashika El Ridi, Hatem Tallima
doaj   +1 more source

Pharmacological and immunological effects of praziquantel against Schistosoma japonicum: a scoping review of experimental studies

open access: yesInfectious Diseases of Poverty, 2018
BackgroundChemotherapy for schistosomiasis has been around for 100 years. During the past century, great efforts have been made to develop new antischistosomal drugs from antimonials to nonantimonials, and some of these have been used extensively in ...
S. Xiao, Jun Sun, Ming-gang Chen
semanticscholar   +1 more source

Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum

open access: yesMolecules, 2013
The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described.
Chuan-Xin Yu   +7 more
doaj   +1 more source

Five-year impact of repeated praziquantel treatment on subclinical morbidity due to Schistosoma japonicum in China [PDF]

open access: yes, 2017
We report the 5-year impact (1996-2001) of repeated praziquantel chemotherapy on subclinical morbidity related to Schistosoma japonicum infection. We repeated stool examinations and hepatosplenic ultrasonography in a cohort of 120 individuals living on ...
Dessein, A.   +6 more
core  

Colon polyps with or without Schistosoma japonicum

open access: yesRevista Española de Enfermedades Digestivas
Schistosoma japonicum, which has been endemic for a long time, associated colon abnormality has also been sporadically reported. The majority of patients with Schistosomiasis japonicum infected may mainly presented as acute manifestation or become chronic complication, known as schistosomiasis liver change, intestinal tract lesions and other system ...
Youhong, Cao, Chen, Yuan
openaire   +2 more sources

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