Results 61 to 70 of about 15,657 (202)

Patent Landscape of Helminth Vaccines and Related Technologies [PDF]

open access: yes, 2013
Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths.
Burke, Rayna   +4 more
core   +1 more source

In Vitro Effects of Vanadate Erbium/Silver Oxide (ErVO4/AgO) and Vanadate Iron/Silver Oxide (FeVO4/AgO) Nanoparticles on the Adult of Fasciola hepatica

open access: yesVeterinary Medicine and Science, Volume 11, Issue 3, May 2025.
ABSTRACT Fascioliasis is a common hepatic parasitic disease that is caused by Fasciola, resulting in significant economic losses by reducing production and consigning viscera in animals. Currently, there is little research regarding the impact of chemical compounds on the ultrastructure and motility of adult F. hepatica.
Arbabi Mohsen   +5 more
wiley   +1 more source

Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum

open access: yesParasites & Vectors, 2014
Background In the process of hepatic fibrosis, hepatic stellate cells (HSCs) can be activated by many inflammatory cytokines. The transforming growth factor-β1 (TGF-β1) is one of the main profibrogenic mediators.
Dandan Zhu   +10 more
doaj   +1 more source

A Novel Chitin‐Based Purification System Using GAL1 Fusion Tags: Enhancing Recombinant Protein Production While Retaining Biological Activity

open access: yesMicrobial Biotechnology, Volume 18, Issue 5, May 2025.
A chitin‐based affinity chromatography system using GAL1 as a fusion tag efficiently purifies recombinant proteins while retaining their biological activity, offering a cost‐effective alternative to conventional purification methods. ABSTRACT Efficient and economical purification methods are crucial for the commercial production of recombinant proteins
Yao‐Kuang Tseng   +7 more
wiley   +1 more source

Development of monoclonal antibodies against Sj29 and its possible application for schistosomiasis diagnosis

open access: yesInternational Journal of Infectious Diseases, 2017
Objective: Timely Schistosoma japonicum detection improves outcomes in schistosomiasis. Here, we established a double antibody sandwich ELISA to detect Schistosoma japonicum.
Cui-Ping Ren   +9 more
doaj   +1 more source

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

open access: yesPLoS Neglected Tropical Diseases, 2022
Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not.
Jia Shen   +6 more
doaj   +1 more source

Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets. [PDF]

open access: yesPLoS Computational Biology, 2014
Blood fluke proteases play pivotal roles in the processes of invasion, nutrition acquisition, immune evasion, and other host-parasite interactions. Hundreds of genes encoding putative proteases have been identified in the recently published schistosome ...
Shuai Liu   +7 more
doaj   +1 more source

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]

open access: yes, 2019
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing   +5 more
core   +2 more sources

Assembly and Functionality of 2D Protein Arrays

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
2D protein arrays‐based outstanding properties, including their remarkable structural stability, exceptional physiochemical properties, and tunable electronic and mechanical attributes, have become a key functional platform for developing advanced functional materials.
Mingming Du   +6 more
wiley   +1 more source

Development of a novel real-time polymerase chain reaction assay for the sensitive detection of Schistosoma japonicum in human stool.

open access: yesPLoS Neglected Tropical Diseases, 2021
BackgroundElimination and control of Schistosoma japonicum, the most virulent of the schistosomiasis-causing blood flukes, requires the development of sensitive and specific diagnostic tools capable of providing an accurate measurement of the infection ...
Sara Halili   +4 more
doaj   +1 more source

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