Results 61 to 70 of about 48,598 (201)
Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata [PDF]
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
Crickmore, Neil+6 more
core +2 more sources
Objective: To develop a new sandwich based lateral flow immunochromatographic strip for rapid detection of circulating Schistosoma mansoni antigen in serum and urine samples of patients with active schistosomiasis.
Manal Kamel+7 more
doaj +1 more source
Fucosyltransferases in Schistosoma mansoni development [PDF]
Glycoconjugate-bound fucose, abundant in the parasite Schistosoma mansoni, has been found in the form of Fucalpha1,3GlcNAc, Fucalpha1,2Fuc, Fucalpha1,6GlcNAc, and perhaps Fucalpha1,4GlcNAc linkages. Here we quantify fucosyltransferase activities in three developmental stages of S. mansoni.
Mette Strand+5 more
openaire +3 more sources
ABSTRACT Background and Aims Intestinal parasites and malnutrition are major public health challenges in Ethiopia, highlighting the need for local epidemiological data to inform effective prevention and intervention strategies. This study aimed to assess the prevalence of intestinal parasitic infection, undernutrition, and their associated risk factors
Abera Ademasu Birhanu+3 more
wiley +1 more source
GPCR and IR genes in Schistosoma mansoni miracidia
Background Schistosoma species are responsible for the disease schistosomiasis, a highly prevalent helminthic disease that requires a freshwater snail as intermediate host. The S.
Di Liang+4 more
doaj +1 more source
The Schistosoma mansoni transcriptome: An update [PDF]
Large scale EST sequencing projects have been carried out for Schistosoma mansoni and Schistosoma japonicum. This update will briefly review the most recent accomplishments in the area and discuss the use of EST data for the purposes of gene discovery, gene model development, genome annotation and SNP analysis. In addition, the use of ESTs for studying
openaire +3 more sources
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier+26 more
wiley +1 more source
BackgroundMalaria and schistosomiasis are among the most important parasitic diseases with overlapping geographical distribution in Ethiopia. The objective of this study, therefore, was to assess parasitological and clinical correlates and determinants ...
Kemal Mohamed+2 more
doaj +1 more source
Gerações de Biomphalaria glabrata e Biomphalaria tenagophila selecionadas geneticamente para resistência e suscetibilidade ao Schistosoma mansoni das linhagens BH e SJ foram utilizadas no estudo da adaptação do trematódeo ao hospedeiro intermediário.
Nádia Regina Borim Zuim+3 more
doaj +1 more source
Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins
The synthesis of triterpenoid saponins bearing a Lewis‐X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin‐targeted therapeutic applications, are prepared through iterative and ...
Oscar Javier Gamboa Marin+3 more
wiley +1 more source