Results 61 to 70 of about 66,712 (259)

Prevalence and Predictors Associated to Schistosoma mansoni Infection among Patients Attending the Saint Jean de Malte Hospital, Njombe, Littoral Region, Cameroon

Journal of Parasitology Research, 2023
Background. Schistosomiasis remains a major public health concern in sub-Saharan Africa. It has been associated to morbidity and mortality in developing countries including Cameroon, and Njombe-Penja health district is an endemic area.
Ambe Fabrice Ngwa, Pride Tanyi Bobga, Ekwi Damian Nsongmayi, Gedeon Schadrack Yememe Yememe, Judith Ngong Nyeme, Mohamed Isah, Ebai Christabel Ashu, Calvin Bisong Ebai   +7 more
doaj   +1 more source

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

Plant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg, Geartsje M. Bakker, Alex van der Kaaij, Élyse Gariépy, Henri van de Geest, Erik J. Slootweg, Ferdinand C. O. Los, Lotte B. Westerhof, Ruud H. P. Wilbers   +8 more
wiley   +1 more source

Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis.

Journal of Medicinal Chemistry, 2016
Schistosomiasis is a major neglected parasitic disease that affects more than 265 million people worldwide and for which the control strategy consists of mass treatment with the only available drug, praziquantel.
T. Heimburg, A. Chakrabarti, Julien Lancelot, M. Marek, Jelena Melesina, Alexander-Thomas Hauser, T. Shaik, S. Duclaud, D. Robaa, F. Erdmann, Matthias Schmidt, C. Romier, R. Pierce, M. Jung, W. Sippl   +14 more
semanticscholar   +1 more source

Development of new lateral-flow immunochromatographic strip using colloidal gold and mesoporous silica nanoparticles for rapid diagnosis of active schistosomiasis

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To develop a new sandwich based lateral flow immunochromatographic strip for rapid detection of circulating Schistosoma mansoni antigen in serum and urine samples of patients with active schistosomiasis.
Manal Kamel, Faten Salah, Zeinab Demerdash, Sara Maher, Shimaa Atta, Abeer Badr, Ahmed Afifi, Hanan El Baz   +7 more
doaj   +1 more source

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

The Schistosoma mansoni transcriptome: An update [PDF]

Experimental Parasitology, 2007
Large scale EST sequencing projects have been carried out for Schistosoma mansoni and Schistosoma japonicum. This update will briefly review the most recent accomplishments in the area and discuss the use of EST data for the purposes of gene discovery, gene model development, genome annotation and SNP analysis. In addition, the use of ESTs for studying
openaire   +3 more sources

Fucosyltransferases in Schistosoma mansoni development [PDF]

Glycobiology, 2001
Glycoconjugate-bound fucose, abundant in the parasite Schistosoma mansoni, has been found in the form of Fucalpha1,3GlcNAc, Fucalpha1,2Fuc, Fucalpha1,6GlcNAc, and perhaps Fucalpha1,4GlcNAc linkages. Here we quantify fucosyltransferase activities in three developmental stages of S. mansoni.
Mette Strand, Yoshitaka Ichikawa, J. T. August, Ronald L. Schnaar, Ernesto T. A. Marques, Gerald W. Hart   +5 more
openaire   +3 more sources

Comparison of Schistosoma mansoni Prevalence and Intensity of Infection, as Determined by the Circulating Cathodic Antigen Urine Assay or by the Kato-Katz Fecal Assay: A Systematic Review

American Journal of Tropical Medicine and Hygiene, 2016
The relationship between results from Kato-Katz (KK) fecal microscopy and urine-based point-of-care circulating cathodic antigen (POC-CCA) assays for Schistosoma mansoni infection remains a critical issue.
Nupur D. Kittur, J. Castleman, C. Campbell, C. King, D. Colley   +4 more
semanticscholar   +1 more source

Seleção genética de Biomphalaria glabrata e Biomphalaria tenagophila visando a alteração da suscetibilidade e resistência ao Schistosoma mansoni Genetic selection of Biomphalaria glabrata and Biomphalaria tenagophila seeking the alteration of the susceptibility and resistance to the Schistosoma mansoni

Revista da Sociedade Brasileira de Medicina Tropical, 2005
Gerações de Biomphalaria glabrata e Biomphalaria tenagophila selecionadas geneticamente para resistência e suscetibilidade ao Schistosoma mansoni das linhagens BH e SJ foram utilizadas no estudo da adaptação do trematódeo ao hospedeiro intermediário.
Nádia Regina Borim Zuim, Eliana Maria Zanotti-Magalhães, Luiz Augusto Magalhães, Arício Xavier Linhares   +3 more
doaj   +1 more source

A nationwide retrospective study of the seroprevalence and risk factors of transfusion‐transmissible infections among blood donors in Nigeria

Transfusion Medicine, EarlyView.
Abstract Background Blood transfusion's life‐saving potential is often marred by the risks of transfusion‐transmissible infections (TTIs) from blood donors, for which sub‐Saharan African countries record some of the highest burdens. Aims We aimed to assess the seroprevalence of HBV, HCV, HIV, and Treponema pallidum among blood donors in Nigeria, and ...
Adaeze Oreh, Felix Biyama, Tariere Bozegha, Joshua Fapohunda, Ifeanyi Mgbachi, Victoria Dalyop, Joy Elisha, Folashade Olupitan, Audu Isaiah, Catherine Babalola, Abdullahi Malammadori, Emmanuel Agahiu, Deborah Kure, Caroline Imonikhe, Chinonso Elesie, Ajoke E. Ogedegbe, Ukinebo Omokaro, Jerry Egbeaso, Chika Oparah, Omale Amedu, Maarten Postma, Theresa Nwagha, Marinus van Hulst   +22 more
wiley   +1 more source