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Schistosomiasis [PDF]

open access: yesThe Lancet, 2018
AbstractSchistosomiasis is a parasitic disease that affects millions of people in 78 countries, where it is held responsible for considerable morbidity and mortality. It is caused by a blood fluke, which provokes an immunological response to hundreds of its antigens.
D. McManus   +5 more
semanticscholar   +9 more sources

The Immunology of Schistosomiasis [PDF]

open access: green, 1976
Publisher Summary This chapter discusses the immunology of schistosomiasis. The only developments relating to innate immunity refer to the death of cercariae in the skin. Concomitant immunity has been shown to operate in a number of experimental systems, and there are encouraging reports that it may operate in human infections.
S. R. Smithers, R. J. Terry
openalex   +5 more sources

Molecular and functional characterization of Schistosoma japonicum annexin A13

open access: yesVeterinary Research, 2023
Schistosomiasis is a neglected tropical disease that affects humans and animals in tropical and subtropical regions worldwide. Schistosome eggs are responsible for the pathogenesis and transmission of schistosomiasis, thus reducing egg production is ...
Haoran Zhong   +11 more
doaj   +1 more source

From Inflammation to Fibrosis: Novel Insights into the Roles of High Mobility Group Protein Box 1 in Schistosome-Induced Liver Damage

open access: yesPathogens, 2022
Schistosomiasis is a chronic helminthic disease of both humans and animals and the second most prevalent parasitic disease after malaria. Through a complex migration process, schistosome eggs trapped in the liver can lead to the formation of granulomas ...
Haoran Zhong   +4 more
doaj   +1 more source

Schistosomiasis Morbidity Hotspots: Roles of the Human Host, the Parasite and Their Interface in the Development of Severe Morbidity

open access: yesFrontiers in Immunology, 2021
Schistosomiasis is the second most important human parasitic disease in terms of socioeconomic impact, causing great morbidity and mortality, predominantly across the African continent.
Patrice A. Mawa   +4 more
semanticscholar   +1 more source

The Dynamics of Hepatic Fibrosis Related to Schistosomiasis and Its Risk Factors in a Cohort of China

open access: yesPathogens, 2021
China has had a long history against schistosomiasis japonica. The most serious prognosis of chronic schistosome infection is hepatic fibrosis, which develops into advanced schistosomiasis if the process is not effectively controlled.
Fei Hu   +9 more
doaj   +1 more source

Spatio-temporal variations of emerging sites infested with schistosome-transmitting Oncomelania hupensis in Hunan Province, China, 1949–2016

open access: yesParasites & Vectors, 2021
Background Constant emerging sites infested with Oncomelania hupensis (O. hupensis) impede the goal realization of eliminating schistosomiasis. The study assessed the spatial and temporal distributions of new Oncomelania snail habitats in Hunan Province ...
Shengming Li   +13 more
doaj   +1 more source

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