Results 1 to 10 of about 6,943 (138)
Cloning and Characterisation of Schistosoma japonicum Insulin Receptors
PLoS ONE, 2010 Schistosomes depend for growth and development on host hormonal signals, which may include the insulin signalling pathway. We cloned and assessed the function of two insulin receptors from Schistosoma japonicum in order to shed light on their role in schistosome biology.We isolated, from S. japonicum, insulin receptors 1 (SjIR-1) and 2 (SjIR-2) sharing
Hong You +2 more
exaly +8 more sources
Hemolytic factors in Schistosoma japonicum eggs [PDF]
Infection and Immunity, 1984 Extracts of Schistosoma japonicum eggs were found to exhibit hemolytic activity on erythrocytes of various species. The hemolytic reaction took place more rapidly at 37 degrees C than at 4 degrees C and did not require divalent cations. The degree of hemolysis was dependent on the concentration of the egg extracts.
H, Asahi +3 more
openaire +2 more sources
Schistosoma japonicum Associated With Colorectal Cancer
ACG Case Reports Journal, 2021 ABSTRACT Colorectal cancer (CRC) is one of the most common cancers worldwide, with increasing prevalence in Asian countries with a crude incidence of 21.1 per 100,000. Schistosoma is a genus of trematodes that infect millions of humans, affecting multiple organs, notably the intestines, liver, and bladder.
Almoghrabi, Anas +2 more
openaire +2 more sources
Functional characterisation of Schistosoma japonicum acetylcholinesterase [PDF]
Parasites & Vectors, 2016 Acetylcholinesterase (AChE) is an important metabolic enzyme of schistosomes present in the musculature and on the surface of the blood stage where it has been implicated in the modulation of glucose scavenging from mammalian host blood. As both a target for the antischistosomal drug metrifonate and as a potential vaccine candidate, AChE has been ...
You, Hong +6 more
openaire +6 more sources
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Progress and Challenges in Phylogenomics and Genomics of Lophotrochozoa/Spiralia
Zoologica Scripta, EarlyView.ABSTRACT Lophotrochozoa is one of the three major bilaterian groups comprising more than half of the bilaterian phyla. Lophotrochozoa includes among others Mollusca, Annelida, Platyhelminthes and Rotifera. Despite representing such a large proportion of animal diversity, they are historically understudied and genomic resources have been scarce. However,
Torsten H. Struck
wiley +1 more source
Journal of Biophotonics, Volume 19, Issue 6, June 2026.Second Harmonic Generation and Two‐Photon Excitation Fluorescence microscopy allows to characterize mice tissues infected with Schistosoma mansoni in an experimental model. ABSTRACT Schistosomiasis is a neglected disease caused by parasites of the genus Schistosoma that poses serious public health problems.
Gladystone Rocha da Fonseca +6 more
wiley +1 more source
A Case for Anti‐IgE Vaccination
Allergy, Volume 81, Issue 6, Page 2001-2013, June 2026.ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.Liver alterations induced by single infection (SI) or reinfection (RE) with 250 or 2500 Ascaris suum eggs in mice. Histological analysis shows inflammatory cell infiltration (eosinophils, lymphocytes, macrophages, and neutrophils), fibrotic areas, and bile duct proliferation in infected animals compared with uninfected controls.
Jorge Lucas Nascimento Souza +16 more
wiley +1 more source