Effects of Different Living Environments on Intestinal Flora in Patients With Schistosoma Japonicum‐Induced Liver Fibrosis [PDF]
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Different living environments have a significant impact on the gut microbiota of patients with Schistosoma japonicum. ABSTRACT Schistosomiasis japonica is a parasitic disease leading to liver cirrhosis. China's “fishermen going ashore” policy divides patients with schistosomiasis liver fibrosis into two groups: those near the infected waters and those ...
Xiaofei Fan +3 more
wiley +2 more sources
Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development [PDF]
Advanced Science, Volume 13, Issue 53, 24 September 2026.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +2 more sources
Optimisation and analytical assessment of a TaqMan™ probe-based real-time PCR assay designed to diagnose infection with Schistosoma japonicum [PDF]
Parasites & VectorsBackground Intestinal schistosomiasis, caused by infection with Schistosoma japonicum, remains a zoonotic neglected tropical disease (NTD) of significant public health importance in parts of China, the Philippines, and Indonesia.
John Archer +5 more
doaj +2 more sources
Species-specific detection of Schistosoma japonicum using the ‘SNAILS’ DNA-based biosensor [PDF]
Communications BiologyThe neglected tropical disease schistosomiasis continues to be a global health concern, especially in low- and middle-income countries, with at least 250 million people infected worldwide and a further 779 million at risk of infection.
Alexander J. Webb +5 more
doaj +2 more sources
A Magnetic-Assisted CRISPR-Cas12a Biosensor Incorporating a Y-DNA Probe for Sensitive Detection of Schistosoma japonicum Eggs [PDF]
BiosensorsSchistosomiasis, caused by Schistosoma species, is notoriously difficult to accurately diagnose with conventional methods. In this study, we present an innovative biosensor that integrates CRISPR–Cas12a technology with nucleic acid aptamers for the ...
Ting Liu +7 more
doaj +2 more sources
Histopathological Study of Wistar Rat Liver Infected with Schistosoma japonicum [PDF]
WMJ (Warmadewa Medical Journal)Schistosoma, including Schistosoma japonicum (S. japonicum), can live with an intermediate host, such as rats, and infect mammals, such as humans and rats. We can use a rat model to understand the pathophysiology of Schistosoma. The aim of this study is
David Pakaya +4 more
doaj +2 more sources
Memorias do Instituto Oswaldo Cruz, 1987 We have been able to produce a mouse monoclonal IgE antibody specific to an adult worm antigen extracted from Schistosoma japonicum (Sj). The antibody was able to elicit passive cutaneous anaphylaxis in the rat skin against Sj with the highest titer of 1:
Somei Kojima +3 more
doaj +2 more sources
Evaluation of Suitable Reference Gene During the Development of Paired or Unpaired Female Schistosoma japonicum on the 18th and the 23rd Days Post Infection [PDF]
PathogensBackground: Identifying optimal housekeeping genes is essential to accurately quantify gene expression dynamics across the 18th day (male and female begin to pair) and the 23rd day (female begin to sex mature) post infection of Schistosoma japonicum ...
Suwen Wang, Liang Feng, Jun Sun
doaj +2 more sources
Cloning and Characterisation of Schistosoma japonicum Insulin Receptors [PDF]
PLoS ONE, 2010 Schistosomes depend for growth and development on host hormonal signals, which may include the insulin signalling pathway. We cloned and assessed the function of two insulin receptors from Schistosoma japonicum in order to shed light on their role in schistosome biology.We isolated, from S. japonicum, insulin receptors 1 (SjIR-1) and 2 (SjIR-2) sharing
You, Hong +10 more
openaire +8 more sources
An Evaluation of Cross-Program and Program-System Integration of Five National Public Health Programs and the Health System in Cambodia: a Review of the Literature. HIV/AIDS, tuberculosis, malaria, reproductive health and immunization. [PDF]
, 2010 Background: The aim of this study was to spatially model the effect of demographic, reservoir hosts and environmental factors on human Schistosoma japonicum infection prevalence in the Dongting Lake area of Hunan Province, China and to determine the ...
Balen, J, Johnson, H, Finch, T, Coker, R
core +4 more sources