Results 11 to 20 of about 51,687 (226)

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goal for schistosomiasis [version 2; peer review: 2 approved, 1 approved with reservations] [PDF]

open access: yesGates Open Research, 2019
Schistosomiasis remains one of the neglected tropical diseases (NTDs) impacting millions of people around the world. The World Health Organization (WHO) recently proposed a goal of elimination as a public health problem (EPHP) for schistosomiasis to be ...
NTD Modelling Consortium Schistosomiasis Group
doaj   +4 more sources

Unusual Spinal Epidural and Paraspinal Venous Engorgement Secondary to Hepatosplenic Schistosomiasis: A Rare Cause of Severe Low Back Pain. [PDF]

open access: yesClin Case Rep
ABSTRACT Severe low back pain from spinal epidural and paraspinal venous engorgement secondary to hepatosplenic schistosomiasis is rare. MRI revealed dilated epidural veins and neural foraminal narrowing. The patient was managed conservatively with analgesia and carvedilol for portal hypertension and subsequently experienced complete resolution of back
Birara ED   +8 more
europepmc   +2 more sources

Schistosomiasis [PDF]

open access: yesThe Lancet, 2018
Schistosomiasis (bilharzia) is a neglected tropical disease caused by parasitic flatworms (blood flukes) of the genus Schistosoma, with considerable morbidity in parts of the Middle East, South America, Southeast Asia and, particularly, in sub-Saharan Africa. Infective larvae grow in an intermediate host (fresh-water snails) before penetrating the skin
McManus, D. P.   +5 more
  +8 more sources

miR-181a regulates the host immune response against Schistosoma japonicum infection through the TLR4 receptor pathway

open access: yesParasites & Vectors, 2021
Background Schistosomiasis japonica is a serious zoonotic parasitic disease. Preliminary studies have shown that the expression of microRNA-181a (miR-181a) in the liver, lung and spleen tissues of susceptible host BALB/c mice and resistant host reed vole
Yixiao Tang   +8 more
doaj   +1 more source

Sja-Let-7 Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in a Mouse Model via Col1α2

open access: yesBiology, 2023
Liver fibrosis (LF) is a chronic progressive disease with no definitive treatment. The aim of this study was to assess helminth-derived molecules as potential therapeutic targets to prevent or reverse LF.
Haoran Zhong   +7 more
doaj   +1 more source

Characterisation and preliminary functional analysis of N-acetyltransferase 13 from Schistosoma japonicum

open access: yesBMC Veterinary Research, 2021
Background N-acetyltransferase 13 (NAT13) is a probable catalytic component of the ARD1A-NARG1 complex possessing alpha (N-terminal) acetyltransferase activity.
Yalan Tang   +12 more
doaj   +1 more source

From Inflammation to Fibrosis: Novel Insights into the Roles of High Mobility Group Protein Box 1 in Schistosome-Induced Liver Damage

open access: yesPathogens, 2022
Schistosomiasis is a chronic helminthic disease of both humans and animals and the second most prevalent parasitic disease after malaria. Through a complex migration process, schistosome eggs trapped in the liver can lead to the formation of granulomas ...
Haoran Zhong   +4 more
doaj   +1 more source

Molecular and functional characterization of Schistosoma japonicum annexin A13

open access: yesVeterinary Research, 2023
Schistosomiasis is a neglected tropical disease that affects humans and animals in tropical and subtropical regions worldwide. Schistosome eggs are responsible for the pathogenesis and transmission of schistosomiasis, thus reducing egg production is ...
Haoran Zhong   +11 more
doaj   +1 more source

The Dynamics of Hepatic Fibrosis Related to Schistosomiasis and Its Risk Factors in a Cohort of China

open access: yesPathogens, 2021
China has had a long history against schistosomiasis japonica. The most serious prognosis of chronic schistosome infection is hepatic fibrosis, which develops into advanced schistosomiasis if the process is not effectively controlled.
Fei Hu   +9 more
doaj   +1 more source

Schistosomiasis [PDF]

open access: yesDigestion, 1998
Schistosomiasis is a man-made disease related to water contact in the agricultural fields and affecting millions of people in developing countries in the tropical and subtropical parts of Africa, Asia and South America. It is a bisexual trematode living in the portal blood and perivesical venous plexus.
  +7 more sources

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