Results 51 to 60 of about 46,909 (203)
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Frederik Stettler+18 more
wiley +1 more source
Identification and Evaluation of the Urinary Microbiota Associated With Bladder Cancer
Urinary microbiota in Chinese bladder cancer patients reveals distinct profiles between non‐muscle‐invasive and muscle‐invasive diseases, with potential biomarkers like Peptoniphilus spp. in high‐risk MIBC, suggesting a role in cancer progression. Dysbiosis may serve as a stratification marker for bladder cancer risk. ABSTRACT Background Bladder cancer
Nannan Li+11 more
wiley +1 more source
Schistosomal infestation of the central nervous system is a rare cause of cord compression, although a predominant one in endemic areas.A 38-year-old male, native of Ivory Coast, with a history of 1 month of progressive paraparesis, neurogenic bladder, diminished deep tendon reflexes of the lower limbs, and sensory level. The magnetic resonance imaging
Pappamikail, L+2 more
openaire +3 more sources
Background Plasmodium vivax is the most widely distributed malaria parasite, and its drug resistance poses unique challenges to malaria elimination. The Greater Mekong Subregion (GMS) is known as the global epicenter of multidrug resistance. Surveillance
Xiaoxiao Wang+5 more
doaj +1 more source
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper+3 more
wiley +1 more source
The stereochemical diversity of the “glycan code” enables similar chiral motifs to arise from both D‐ and L‐sugars. Focused on DC‐SIGN–glycan recognition, two diverse monosaccharide scaffolds, D‐Man (D‐Rha) and L‐Gal (L‐Fuc), maintain the exquisite stereochemistry encoded in the minimal binding epitope.
J. Daniel Martínez+7 more
wiley +1 more source
Schistosomiasis japonicum can cause different degrees of organ damage and complex human immune pathological reactions, which often invade the intestine and liver. The purpose of this study was to explore the pathological types and pathological changes of
Yang Yang+7 more
doaj +1 more source
Clinical Evaluation of the Healgen Rapid COVID‐19 Antigen Test as a Point‐of‐Care Diagnostic Tool
ABSTRACT Background Development of readily available Rapid COVID‐19 Antigen tests essential for promptly identifying SARS‐CoV2 infection and preventing its spread. Methods This study evaluated the clinical performance of the Healgen Rapid COVID‐19 antigen test as a point‐of‐care diagnostic tool with 806 evaluable subjects who were within 6 days post ...
Stephen A. Young+10 more
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier+26 more
wiley +1 more source