Results 51 to 60 of about 30,691 (180)

The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng   +3 more
wiley   +1 more source

Paperdemic and Its Preventive Measures: A Case Study of COVID-19

open access: yesYixue yu zhexue
During the COVID-19 pandemic, a large number of research resources and focus had shifted to virus-related fields, resulting in a rapid surge in scientific outputs.
Yao DENG, Li PAN, Wei WANG
doaj   +1 more source

Upon entering an age of global ivermectin-based integrated mass drug administration for neglected tropical diseases and malaria

open access: yesMalaria Journal, 2017
Ivermectin mass drug administration (MDA) in humans to reduce malaria vectors is yet another use for this remarkable medicine whose discoverers shared the 2015 Nobel Prize in Medicine with the discoverer of artemisinin.
Frank O. Richards
doaj   +1 more source

A New Method to Test Molluscicides against the Philippine Schistosomiasis Snail Vectors

open access: yesJournal of Parasitology Research, 2020
To expedite the discovery of novel molluscicides in the laboratory, this study aimed to evaluate the performance of a new molluscicidal assay. This assay is based on Oncomelania hupensis quadrasi snails and is called miniaturized plate test or mpt.
Darwin C. Gomez, Neil Anacta
doaj   +1 more source

Clinical Practice of Pulmonary Arterial Hypertension (PAH) and Potential Barriers to Intensive Treatment Among PAH‐Specialized and Non‐PAH‐Specialized Centers in Japan

open access: yesPulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a rare and progressive disease characterized by remodeling of the pulmonary vasculature, which leads to increased pulmonary artery pressure and ultimately right ventricular failure. Although Japanese guidelines recommend combination therapy, real‐world data show inconsistencies in its implementation. We
Yoko Arai   +4 more
wiley   +1 more source

Activin Signaling Inhibitors in Pulmonary Hypertension: A State‐of‐the‐Art Review

open access: yesPulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a disease of abnormal pulmonary vascular remodeling and vascular obliteration that results in right heart failure and death. PAH pathogenesis is strongly associated with mutations of the Transforming Growth Factor Beta (TGF‐β) superfamily signaling pathway, which has previously been challenging to ...
Sudarshan Rajagopal   +10 more
wiley   +1 more source

Schistosoma japonicum Worms Alter the miRNA Expression Profile of Hepatic Stellate Cells with Potential Implications for Liver Fibrosis and Hepatocellular Carcinoma

open access: yesTropical Medicine and Infectious Disease
Although schistosome eggs are widely recognized as the principal drivers of hepatic granulomatous inflammation and fibrosis, the independent effects of adult worms may be masked by strong egg antigen-mediated responses.
Haoran Zhong   +11 more
doaj   +1 more source

Poverty and Social Deprivation in Patients With Pulmonary Arterial Hypertension—A PHAR Analysis

open access: yesPulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Poverty and social deprivation have been associated with impaired clinical outcomes and survival in several chronic diseases. The association between poverty and clinical outcomes in patients with pulmonary arterial hypertension (PAH) remains unclear.
Roberto J. Bernardo   +12 more
wiley   +1 more source

Identification of optimum scopes of environmental factors for snails using spatial analysis techniques in Dongting Lake Region, China

open access: yesParasites & Vectors, 2014
Background Owing to the harmfulness and seriousness of Schistosomiasis japonica in China, the control and prevention of S. japonica transmission are imperative. As the unique intermediate host of this disease, Oncomelania hupensis plays an important role
Jin-Yi Wu   +11 more
doaj   +1 more source

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, Volume 78, Issue 8, Page 959-966, August 2026.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

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