Results 91 to 100 of about 96,030 (249)
Inhibition of Notch Signaling Attenuates Schistosomiasis Hepatic Fibrosis via Blocking Macrophage M2 Polarization. [PDF]
PLoS ONE, 2016 Macrophages play a key role in the pathogenesis of liver granuloma and fibrosis in schistosomiasis. However, the underlying mechanisms have not been fully characterized.
Shaoping Zheng +5 more
doaj +1 more source
Research Progress Report on Microtus fortis as a New Resource of Laboratory Animal
Shiyan dongwu yu bijiao yixue, 2023 Microtus fortis (reed vole) is the only mammal known to have natural resistance to Schistosomiasis japonica. Originating from schistosomiasis endemic and non-endemic areas, as well as laboratory bred voles have the same resistance to Schistosoma ...
XIE Jianyun
doaj +1 more source
AUTOIMMUNITY IN SCHISTOSOMIASIS JAPONICA
The Kurume Medical Journal, 1966 Schistosomiasis japonica occurs in specific areas of Asia and is caused by an infection of Schistosoma japonicum. Immunohematological investigations of the significance of autoimmunity in general symptoms of schistosomiasis japonica have been performed with use of experimentally infected rabbits.
openaire +4 more sources
Opportunities and challenges for modelling epidemiological and evolutionary dynamics in a multihost, multiparasite system: Zoonotic hybrid schistosomiasis in West Africa [PDF]
, 2017 Multihost multiparasite systems are evolutionarily and ecologically dynamic, which presents substantial trans‐disciplinary challenges for elucidating their epidemiology and designing appropriate control.
Borlase, A, Rudge, J W, Webster, J P
core +3 more sources
Contrasting reservoirs for Schistosoma japonicum between marshland and hilly regions in Anhui, China--a two-year longitudinal parasitological survey. [PDF]
, 2009 Schistosoma japonicum remains highly endemic in many counties in China and has recently re-emerged, to a large extent, in previously controlled areas. To test the hypothesis that small rodents and less agriculturally important domestic animals such as ...
Donnelly, Christl A +5 more
core +1 more source
Parasites & Vectors, 2011 Background Schistosomiasis japonica remains a major public health concern in China. There are many interventions implemented to control the transmission of the disease.
Sun Le-Ping +8 more
doaj +1 more source
Parasite Immunology, Volume 47, Issue 5, May 2025.ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Chen Zhou, Pengpeng Zhang, Yingzi Ming
wiley +1 more source
Parasites & Vectors, 2015 Background Schistosomiasis is a chronic parasitic disease that affects approximately 200 million people. In Schistosomiasis japonica and mansoni, parasite eggs were trapped in host liver and stimulated the CD4+T cell responses to regulate the formation ...
Weiwei Zhang +13 more
doaj +1 more source
Tropical Medicine and Health, 2018 Background Hepatosplenic lesion formation is one of the typical clinical symptoms of schistosomiasis japonica. Although it is established that circum-oval granuloma formation mediated by T lymphocytes is the key event triggering the formation of hepatic ...
Katsumi Maezawa +4 more
doaj +1 more source
The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism
Animal Models and Experimental Medicine, Volume 8, Issue 1, Page 114-125, January 2025.GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage and hepatocyte vacuolation. The expression of genes involved in the development of liver fibrosis was stronger in the livers of GSDMD‐NTki/wtandAlb‐creki/wt mice. GSDMD‐NT induces fibrosis by mediating lipid metabolism. Abstract Background The emerging incidence of pathogenic liver conditions
Xue Wang +10 more
wiley +1 more source