Results 101 to 110 of about 95,531 (236)

Should we be treating animal schistosomiasis in Africa? The need for a One Health economic evaluation of schistosomiasis control in people and their livestock [PDF]

, 2017
A One Health economic perspective allows informed decisions to be made regarding control priorities and/or implementation strategies for infectious diseases. Schistosomiasis is a major and highly resilient disease of both humans and livestock.
Gower, C M, Vince, L, Webster, J P
core   +1 more source

AUTOIMMUNITY IN SCHISTOSOMIASIS JAPONICA

The Kurume Medical Journal, 1966
Schistosomiasis japonica occurs in specific areas of Asia and is caused by an infection of Schistosoma japonicum. Immunohematological investigations of the significance of autoimmunity in general symptoms of schistosomiasis japonica have been performed with use of experimentally infected rabbits.
openaire   +4 more sources

An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum

Parasites & Vectors, 2015
Background Schistosomiasis is a chronic parasitic disease that affects approximately 200 million people. In Schistosomiasis japonica and mansoni, parasite eggs were trapped in host liver and stimulated the CD4+T cell responses to regulate the formation ...
Weiwei Zhang, Jifeng Zhu, Xian Song, Zhipeng Xu, Xue Xue, Xiaojun Chen, Xiaowei Yang, Yong Li, Xiaoxiao Dong, Sha Zhou, Wei Li, Yingying Qian, Feng Liu, Chuan Su   +13 more
doaj   +1 more source

Real-time observation of pathophysiological processes during murine experimental Schistosoma japonicum infection using high-resolution ultrasound imaging

Tropical Medicine and Health, 2018
Background Hepatosplenic lesion formation is one of the typical clinical symptoms of schistosomiasis japonica. Although it is established that circum-oval granuloma formation mediated by T lymphocytes is the key event triggering the formation of hepatic ...
Katsumi Maezawa, Rieko Furushima-Shimogawara, Akio Yasukawa, Nobuo Ohta, Shiro Iwanaga   +4 more
doaj   +1 more source

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]

, 2019
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing, Buddenborg, Sarah K, Kamel, Bishoy, Loker, Eric S, Mkoji, Gerald M, Zhang, Si-Ming   +5 more
core   +2 more sources

Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy

Parasite Immunology, Volume 47, Issue 5, May 2025.
ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Chen Zhou, Pengpeng Zhang, Yingzi Ming
wiley   +1 more source

Ursolic acid ameliorates CCl4‐induced liver fibrosis through the NOXs/ROS pathway

Journal of Cellular Physiology, Volume 233, Issue 10, Page 6799-6813, October 2018., 2018
UA induces the proliferation of HCs, promotes the apoptosis of HSCs, and prevents the activation of KCs in vivo by reducing the expression of NOXs/ROS in HCs, HSCs, KCs. UA also partly improves phagocytosis of KCs and has no effect on host defense function. Liver fibrosis is a reversible wound‐healing response that occurs after liver injury.
Dakai Gan, Wang Zhang, Chenkai Huang, Jiang Chen, Wenhua He, Anjiang Wang, Bimin Li, Xuan Zhu   +7 more
wiley   +1 more source

Identification of a linear B-cell epitope on the Schistosoma japonicum saposin protein, SjSAP4: Potential as a component of a multi-epitope diagnostic assay.

PLoS Neglected Tropical Diseases, 2022
BackgroundSchistosoma japonicum is one of three major species of blood flukes causing schistosomiasis, a disease, which continues to be a major public health issue in the Philippines.
Yi Mu, Catherine A Gordon, Remigio M Olveda, Allen G Ross, David U Olveda, Jessica M Marsh, Donald P McManus, Pengfei Cai   +7 more
doaj   +1 more source

The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism

Animal Models and Experimental Medicine, Volume 8, Issue 1, Page 114-125, January 2025.
GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage and hepatocyte vacuolation. The expression of genes involved in the development of liver fibrosis was stronger in the livers of GSDMD‐NTki/wtandAlb‐creki/wt mice. GSDMD‐NT induces fibrosis by mediating lipid metabolism. Abstract Background The emerging incidence of pathogenic liver conditions
Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi   +10 more
wiley   +1 more source

IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

Journal of Cellular and Molecular Medicine, Volume 22, Issue 7, Page 3353-3363, July 2018., 2018
Abstract In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fibrosis during schistosomiasis.
Jifeng Zhu, Weiwei Zhang, Lina Zhang, Lei Xu, Xiaojun Chen, Sha Zhou, Zhipeng Xu, Ming Xiao, Hui Bai, Feng Liu, Chuan Su   +10 more
wiley   +1 more source