Results 111 to 120 of about 95,531 (236)

Schistosomiasis Chemotherapy, Chemoprevention, and Vaccines: History, Progress, and Priorities

Immunity, Inflammation and Disease, Volume 12, Issue 11, November 2024.
Schistosomiasis is a major human disease of public health importance. The goal is to provide an overview of the history and advancements in schistosomiasis chemotherapy, chemoprevention, and vaccine research. Praziquantel is effective against all species of schistosomiasis, but schistosomiasis prevalence has largely remained unaffected, due to ...
Alaa Oqalaa E. Alibrahim, Walaa A. Elkholy, Mona M. El‐Derbawy, Noha F. Zahran, Athanasios Alexiou, Marios Papadakis, Gaber El‐Saber Batiha   +6 more
wiley   +1 more source

TLR3 Modulates the Response of NK Cells against Schistosoma japonicum

Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Natural killer (NK) cells are classic innate immune cells that play roles in many types of infectious diseases. NK cells possess many kinds of TLRs that allow them to sense and respond to invading pathogens. Our previous study found that NK cells could modulate the immune response induced by Schistosoma japonicum (S. japonicum) in C57BL/6 mice.
Jiale Qu, Lu Li, Hongyan Xie, Xiaona Zhang, Quan Yang, Huaina Qiu, Yuanfa Feng, Chenxi Jin, Nuo Dong, Jun Huang, Xiaojun Chen   +10 more
wiley   +1 more source

Multi-omics analyses of Bacillus amyloliquefaciens treated mice infected with Schistosoma japonicum reveal dynamics change of intestinal microbiome and its associations with host metabolism.

PLoS Neglected Tropical Diseases
BackgroundSchistosomiasis japonica is a serious threat to human health. It causes damage to the intestine and liver. Probiotic therapy has been shown to be effective in alleviating intestinal diseases and improving host health.
Hao Chen, Shuaiqin Huang, Siqi Yao, Jingyan Wang, Jing Huang, Zheng Yu   +5 more
doaj   +1 more source

Parasite‐derived microRNA let‐7‐5p detection for metacestodiasis based on rolling circular amplification‐assisted CRISPR/Cas9

The FASEB Journal, Volume 38, Issue 10, 31 May 2024.
MicroRNA extraction and RCA‐assisted CRISPR/Cas9 detection. Abstract Metacestodiasis is an infectious disease caused by the larval stage of cestode parasites. This disease poses a serious health hazard to wildlife, livestock, and humans, and it incurs substantial economic losses by impacting the safety of the livestock industry, the quality of meat ...
Liqun Wang, Guiting Pu, Tingli Liu, Guoliang Chen, Hong Li, Tharheer Oluwashola Amuda, Shanling Cao, Hongbin Yan, Hong Yin, Baoquan Fu, Xuenong Luo   +10 more
wiley   +1 more source

A novel immunodiagnostic assay to detect serum antibody response against selected soluble egg antigen fractions from Schistosoma japonicum. [PDF]

PLoS ONE, 2012
BACKGROUND: Schistosomiasis japonica remains a real threat to public health in China. The currently used immunodiagnostic assays are sensitive and have a certain degree of specificity, however, they all use complex crude antigens, are based on detection ...
Yinchang Zhu, Wanquan Hua, Ming Xu, Wei He, Xiaoting Wang, Yang Dai, Song Zhao, Jianxia Tang, Shixia Wang, Shan Lu   +9 more
doaj   +1 more source

MEDICAL GEOGRAPHICAL STUDY ON SCHISTOSOMIASIS JAPONICA

Geographical Review of Japan, 1972
Schistosomiasis japonica is one of the famous endemic disease found in east and southeast Asia. It has been a preventing factor against the social and economical development in the endemic areas. From the above reason this disease can be taken up as a subject of regional study from the view point of medical geography.
Naoko Nihei, Shigeo Asami
openalex   +3 more sources

Vaccines and diagnostics for zoonotic schistosomiasis japonica

Parasitology, 2014
SUMMARYSchistosomiasis is one of the most prevalent, insidious and serious of the tropical parasitic diseases. Although the effective anthelmintic drug, praziquantel, is widely available and cheap, it does not protect against re-infection, drug-resistant schistosome may evolve and mass drug administration programmes based around praziquantel are ...
Donald P. McManus, Hong You
openaire   +3 more sources

Schistosome eggs stimulate reactive oxygen species production to enhance M2 macrophage differentiation and promote hepatic pathology in schistosomiasis.

PLoS Neglected Tropical Diseases, 2021
Schistosomiasis is a neglected tropical disease of public health concern. The most devastating pathology in schistosomiasis japonica and mansoni is mainly attributed to the egg-induced granulomatous response and secondary fibrosis in host liver, which ...
Yanxiong Yu, Junling Wang, Xiaohong Wang, Pan Gu, Zhigang Lei, Rui Tang, Chuan Wei, Lei Xu, Chun Wang, Ying Chen, Yanan Pu, Xin Qi, Beibei Yu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Zhijie Zhang, Sha Zhou, Chuan Su   +18 more
doaj   +1 more source

The contribution of domestic animals to the transmission of schistosomiasis japonica in the Lindu Subdistrict of the Central Sulawesi Province, Indonesia. [PDF]

Vet World, 2019
Background and Aim: Schistosomiasis is endemic in Indonesia and is found in three remote areas in Central Sulawesi Province. Non-human mammals serve as reservoir hosts, meaning the disease is zoonotic. The previous schistosomiasis studies in animals from
Budiono NG, Satrija F, Ridwan Y, Handharyani E, Murtini S.   +4 more
europepmc   +2 more sources

Endemic diseases and agricultural productivity: Challenges and policy response [PDF]

Contrary to Asian countries, the agricultural sector in Africa had not benefited from the green revolution success. After a long time of disinterest in the agriculture sector in Africa, several voices arise now in favour of greater efforts towards this ...
Martine AUDIBERT
core   +3 more sources