Results 1 to 10 of about 22,286 (149)

Analysis of miR‐10a and IFNG Expression Before and After Treatment for Chronic Schistosomiasis mansoni [PDF]

Parasite Immunol
ABSTRACT Mir‐10a acts in signalling pathways regulating transcription, translation, and RNA‐mediated gene silencing, while IFNG acts in the T‐cell receptor signalling pathway. Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis.
da Nóbrega D, Barreto A, dos Santos Souza R, do Ó K, de Lima R, Domingues A, Lopes E, de Morais C, Gomes E, Vasconcelos L.   +9 more
europepmc   +2 more sources

Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium [PDF]

, 2012
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-aged children are also at risk, and hence might need ...
Coulibaly, J. T., Keiser, J., Knopp, S., N'Gbesso, Y. K., N'Goran, E. K., Utzinger, J.   +5 more
core   +35 more sources

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates. [PDF]

Protein Sci
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Silva EB, Jiang Z, Liu C, Fajtová P, Teixeira TR, de Castro Fiorini Maia G, Liu LJ, El-Sakkary N, Skinner DE, Syed A, Wang SC, Caffrey CR, O'Donoghue AJ.   +12 more
europepmc   +2 more sources

Decline in transmission of schistosomiasis mansoni in Oman. [PDF]

Infect Dis Poverty, 2016
Intestinal schistosomiasis due to Schistosoma mansoni was first reported in Oman in 1979. We describe the trend in parasitological and serological prevalence of human infection with S. mansoni in the endemic area over the period 1982-2014, and the compliance of data generated by the national monitoring and evaluation system with schistosomiasis ...
Al Abaidani I, Al-Abri S, Shaban M, Ghugey SL, Al Kathery S, Al-Mashikhi K, Garba A, Gabrielli AF.   +7 more
europepmc   +4 more sources

Seroepidemioplogy of schistosomiasis mansoni [PDF]

Memórias do Instituto Oswaldo Cruz, 1992
In population surveys in which the Schistosoma mansoni intensity of infection is low, or in localities where the schistosomiasis control program had success, the parasitologic methods lack in sensitivity. Despite of some limitations, the immunological methods are useful to provide valuable information in such field conditions.
Hoshino-Shimizu, S., Dias, L. C. S., Kanamura, H. Y., Silva, L. C., Glasser, C. M., Patucci, R. M. J.   +5 more
openaire   +5 more sources

Ultrasound in schistosomiasis mansoni [PDF]

Memórias do Instituto Oswaldo Cruz, 2010
We reviewed ultrasound features in patients with schistosomiasis mansoni. The alterations that we observed in acute and hepatosplenic schistosomiasis are described. The advantages and disadvantages of using ultrasound patterns in the evaluation of liver fibrosis are discussed.
Pinto-Silva, Rogério Augusto, de Queiroz, Leonardo Campos, Azeredo, Letícia Martins, Silva, Luciana Cristina dos Santos, Lambertucci, José Roberto   +4 more
openaire   +4 more sources

Vulvar schistosomiasis mansoni [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2008
: Prof. Jose Roberto Lambertucci. Faculdade de Medicina/UFMG. Avenida Alfredo Balena 190, 30130-100 Belo Horizonte, MG, Brasil.Jose Roberto Lambertucci. Faculdade de Medicina/UFMG. Avenida Alfredo Balena 190, 30130-100 Belo Horizonte, MG, Brasil.e-mail: lamber@uai.com.brRecebido para publicacao em 12/09/2008Aceito em 15/09 ...
José Roberto Lambertucci, Marina De Brot, Izabela Voieta   +2 more
openaire   +3 more sources

The effects of subcurative praziquantel treatment on life-history traits and trade-offs in drug-resistant Schistosoma mansoni [PDF]

, 2016
Natural selection acts on all organisms, including parasites, to maximise reproductive fitness. Drug resistance traits are often associated with life-history costs in the absence of treatment.
Viana, Mafalda, Faust, Christina L., Haydon, Dan T., Webster, Joanne P., Lamberton, Poppy H.L.   +4 more
core   +13 more sources

Schistosomiasis mansoni of the prostate [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2006
A 56-year-old man came to hospital for a routine checkup. His medical history and physical examination wereunremarkable. Laboratory evaluation was normal, except for aserum prostate specific antigen (PSA) of 6.5ng/mL (referencevalues: 0-3.5ng/mL). Digital rectal examination revealed anenlarged well-delimitated prostate.
Alfredo José Afonso Barbosa, Izabela Voieta, José Roberto Lambertucci   +2 more
openaire   +2 more sources

Pulmonary involvement in Schistosomiasis mansoni [PDF]

Memórias do Instituto Oswaldo Cruz, 1987
The post-treatment pulmonary alterations were evaluated in patients (Study 1) and in mice (Study 2) infected with Schistosoma mansoni. Study 1: the patients were examined pre and post-treatment (with ora oxamniquine) and the following exams were performed: sputum for eosinophils and chest x-ray.
Greco, Dirceu B., Pedroso, Enio R. P., Lambertucci, J. R., Rocha, Manoel O. C., Coelho, Paulo Marcos Z., Raso, Pedro, Ferreira, Cid S.   +6 more
openaire   +5 more sources