Results 1 to 10 of about 74,570 (280)

The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni [PDF]

Memorias do Instituto Oswaldo Cruz, 2019
BACKGROUND Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease.
Gilmara Lima Nascimento, Helio Milani Pegado, Ana Lúcia Coutinho Domingues, Ricardo Arraes de Alencar Ximenes, Alexander Itria, Luciane Nascimento Cruz, Maria Regina Fernandes de Oliveira   +6 more
doaj   +3 more sources

Schistosomiasis Mansoni-Recruited Eosinophils: An Overview in the Granuloma Context. [PDF]

Microorganisms, 2022
Eosinophils are remarkably recruited during schistosomiasis mansoni, one of the most common parasitic diseases worldwide. These cells actively migrate and accumulate at sites of granulomatous inflammation termed granulomas, the main pathological feature ...
Malta KK, Palazzi C, Neves VH, Aguiar Y, Silva TP, Melo RCN.   +5 more
europepmc   +2 more sources

Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni. [PDF]

PLoS Neglected Tropical Diseases, 2016
Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated.
Thiago Almeida Pereira, Wing-Kin Syn, Frederico Figueiredo Amâncio, Pedro Henrique Diniz Cunha, Julia Fonseca Morais Caporali, Guilherme Vaz de Melo Trindade, Elisângela Trindade Santos, Márcia Maria Souza, Zilton Araújo Andrade, Rafal P Witek, William Evan Secor, Fausto Edmundo Lima Pereira, José Roberto Lambertucci, Anna Mae Diehl   +13 more
doaj   +2 more sources

Sustaining Control of Schistosomiasis Mansoni in Western Côte d’Ivoire: Results from a SCORE Study, One Year after Initial Praziquantel Administration [PDF]

PLoS Neglected Tropical Diseases, 2016
Background The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) has launched several large-scale trials to determine the best strategies for gaining and sustaining control of schistosomiasis and transitioning toward elimination.
Rufin K Assaré, Yves-Nathan T. Tian-Bi, P. Yao, N. A. N’guessan, M. Ouattara, A. Yapi, J. Coulibaly, Aboulaye Meïté, Eveline Hürlimann, S. Knopp, J. Utzinger, E. N'Goran   +11 more
semanticscholar   +5 more sources

CORRELATION BETWEEN PLATELET COUNT AND BOTH LIVER FIBROSIS AND SPLEEN DIAMETER IN PATIENTS WITH SCHISTOSOMIASIS MANSONI

Arquivos de Gastroenterologia, 2014
Context Studies have described the correlation between platelet count and the stages of fibrosis in chronic viral hepatitis, but few publications have studied this correlation in Schistosomiasis mansoni.
Tibério B MEDEIROS, Ana Lucia C DOMINGUES, Carlos F LUNA, Edmundo P LOPES   +3 more
doaj   +2 more sources

Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation. [PDF]

PLoS ONE, 2013
The aim of this study is to investigate renal markers and the biomarker MCP-1 in patients with schistosomiasis mansoni. This is a cross-sectional study with 85 patients aged 5 to 48 years, with a confirmed diagnosis of schistosomiasis mansoni through the
Ana Lúcia P Hanemann, Alexandre B Libório, Elizabeth F Daher, Alice Maria C Martins, Marta Cristhiany C Pinheiro, Mariana S Sousa, Fernando Schemelzer M Bezerra   +6 more
doaj   +2 more sources

Analysis of miR‐10a and IFNG Expression Before and After Treatment for Chronic Schistosomiasis mansoni [PDF]

Parasite Immunol
ABSTRACT Mir‐10a acts in signalling pathways regulating transcription, translation, and RNA‐mediated gene silencing, while IFNG acts in the T‐cell receptor signalling pathway. Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis.
da Nóbrega D, Barreto A, dos Santos Souza R, do Ó K, de Lima R, Domingues A, Lopes E, de Morais C, Gomes E, Vasconcelos L.   +9 more
europepmc   +2 more sources

Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra-Pubic Mass: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Badri R, Abdalrhim S, Hamid A, Salah Aldeen A, Tahir A, Ahmad MO.   +5 more
europepmc   +2 more sources

A survey of the prevalence of Schistosomiasis among pupils in Apata and Laranto areas in Jos, Plateau State [PDF]

Online Journal of Health & Allied Sciences, 2004
Prevalence of Schistosomiasis in apparently healthy primary school pupils in Apata and Laranto areas of Jos was surveyed using 300 samples of stool and 300 samples of urine.
Okpala HO, Agwu E, Agba MI, Chimezie OR, Nwobu GO, Ohihoin AA   +5 more
doaj   +1 more source

Pharmacological Inhibition of c-Jun N-Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice. [PDF]

Liver Int
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Stettler F, Knedla L, Hagen M, von Bülow V, Müller H, Tschuschner A, Zahner D, Haeberlein S, Moescheid MF, Windhorst A, Burg-Roderfeld M, Glebe D, Moreira BP, Lesieur C, Schmid A, Falcone FH, Grevelding CG, Roeb E, Roderfeld M.   +18 more
europepmc   +2 more sources