The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni [PDF]
BACKGROUND Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease.
Gilmara Lima Nascimento+6 more
doaj +2 more sources
Analysis of miR‐10a and IFNG Expression Before and After Treatment for Chronic Schistosomiasis mansoni [PDF]
ABSTRACT Mir‐10a acts in signalling pathways regulating transcription, translation, and RNA‐mediated gene silencing, while IFNG acts in the T‐cell receptor signalling pathway. Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis.
da Nóbrega D+9 more
europepmc +2 more sources
RE-EVALUATION OF SCHISTOSOMIASIS MANSONI IN MINAS GERAIS, BRAZIL. III. "NOROESTE DE MINAS" MESOREGION [PDF]
This study was conducted to assess the presence of schistosomiasis mansoni in the "Noroeste de Minas" mesoregion, an area considered non-endemic. A malacologic survey and parasitologic stool examinations were undertaken in 13 municipalities of the ...
CARVALHO Omar S.+6 more
doaj +2 more sources
Sigmoid Schistosomiasis Granuloma Manifested as a Large Painless Supra-Pubic Mass: A Case Report. [PDF]
ABSTRACT Schistosomiasis remains a prevalent parasitic disease in tropical and subtropical regions, ranking second to malaria in terms of parasitic burden. The disease manifests in two primary forms: urinary schistosomiasis, caused by Schistosoma haematobium, and intestinal schistosomiasis, associated with S. mansoni and S. japonicum.
Badri R+5 more
europepmc +2 more sources
Pharmacological Inhibition of c-Jun N-Terminal Kinase Activity Exacerbates Liver Damage in Schistosoma mansoni Infected Mice. [PDF]
ABSTRACT Background and Aims Schistosomiasis is a neglected tropical disease affecting more than 250 million people worldwide. Eggs of the parasitic helminth S. mansoni cause major morbidity in the liver, spleen and intestine. Of note, egg‐released soluble antigens (SEA) induce the transcription factor c‐Jun in hepatocytes, promoting hepatocellular ...
Stettler F+18 more
europepmc +2 more sources
A spectral analysis of the myoelectric activity of the left colon in patients with schistosomiasis mansoni [PDF]
The objective of the present study was to perform a spectral analysis of the electrical activity of the left colon of patients with hepatosplenic schistosomiasis. Thirty patients were studied, divided into 2 groups: group A was composed of 14 patients (9
A.A.B. Ferraz
doaj +2 more sources
Schistosoma mansoni granulomas in the skeletal striated muscles in the murine model of neuroschistosomiasis: histological findings [PDF]
Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy.
Thiago Andre Alves Fidelis+8 more
doaj +1 more source
Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni. [PDF]
Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated.
Thiago Almeida Pereira+13 more
doaj +1 more source
Background: Intestinal schistosomiasis is a disease caused by infection with one of the blood flukes called Schistosoma mansoni. The distribution of Schistosoma mansoni infection is high in Sub-Saharan Africa due to water source, sanitation and hygiene ...
Tadesse HAILU+2 more
doaj +1 more source
Background. Vulvar schistosomiasis is a female genital schistosomiasis (FGS), which occurs because of the damage caused by the presence of schistosome ova within the vulva. FGS is mostly misdiagnosed as a sexually transmitted infection.
Anthony Gyening-Yeboah+1 more
doaj +1 more source