Results 1 to 10 of about 75,248 (193)

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

British Journal of Pharmacology, Volume 182, Issue 23, Page 5706-5733, December 2025.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy, Miles J. De Blasio, Owen L. Woodman, Pasquale Maffia, Hong Yong Peh, Cheng Xue Qin   +5 more
wiley   +1 more source

Multidisciplinary Preclinical Investigations on Ferrocenyl, Ruthenocenyl, and Benzyl Derivatives of Niridazole as New Drug Candidates against Schistosomiasis

ChemMedChem, Volume 20, Issue 23, November 28, 2025.
Novel organometallic derivatives of niridazole are designed, synthesized, and tested against Schistosoma mansoni. Schistosomiasis affects hundreds of millions of people worldwide, yet its chemotherapeutic treatment is based on the only drug available‐praziquantel (PZQ).
Tanja Karpstein, Shuai Zhong, Sarah Keller, Philipp Späne, Cécile Häberli, Gordana Panic, Olivier Blacque, Alex Odermatt, Kevin Cariou, Gilles Gasser, Jennifer Keiser   +10 more
wiley   +1 more source

Genital schistosomiasis mansoni concomitant to genital tumor in areas of low endemicity: challenging diagnosis

Brazilian Journal of Infectious Diseases, 2011
Genital infection by Schistosoma mansoni is usually misdiagnosed in individuals who reside in, or travel to endemic areas. We describe two cases of genital tumor associated with S. mansoni infection manifested by methrorragy.
Marta G. Cavalcanti, Margareth M.I. Gonçalves, Magali M. Barreto, Aline Helen da Silva, Kalil Madi, José Mauro Peralta, Ricardo P. Igreja   +6 more
doaj   +1 more source

Ultrasound in schistosomiasis mansoni.

Memórias do Instituto Oswaldo Cruz, 2010
We reviewed ultrasound features in patients with schistosomiasis mansoni. The alterations that we observed in acute and hepatosplenic schistosomiasis are described.
Rogério Augusto Pinto-Silva, Leonardo Campos de Queiroz, Letícia Martins Azeredo, Luciana Cristina dos Santos Silva, José Roberto Lambertucci   +4 more
semanticscholar   +1 more source

Zoonotic Schistosomiasis: The Crossroads Between Animal and Human Schistosomiasis in Africa: Narrative Review

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background The fight against schistosomiasis (urogenital and intestinal) has prolonged more than expected with more areas that were previously known to have less or no incidence of infection now recording alarming incidence rate. Researchers and stakeholders are now concerned about what is probably sustaining the possible infection, and one of
Fatima Amponsah Fordjour, Alexander Kwarteng   +1 more
wiley   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, Volume 25, Issue 21-22, Page 253-276, November 2025.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Effect of maternal Schistosoma mansoni infection and praziquantel treatment during pregnancy on Schistosoma mansoni infection and immune responsiveness among offspring at age five years.

PLoS Neglected Tropical Diseases, 2013
IntroductionOffspring of Schistosoma mansoni-infected women in schistosomiasis-endemic areas may be sensitised in-utero. This may influence their immune responsiveness to schistosome infection and schistosomiasis-associated morbidity.
Robert Tweyongyere, Peter Naniima, Patrice A Mawa, Frances M Jones, Emily L Webb, Stephen Cose, David W Dunne, Alison M Elliott   +7 more
doaj   +1 more source

Schistosomiasis Burden and Its Association With Lower Measles Vaccine Responses in School Children From Rural Cameroon

Frontiers in Immunology, 2018
Background and Methods: Schistosomiasis is debilitating and reported to impair immune responsiveness of infected hosts. In Cameroon, mass drug administration (MDA) is used in schoolchildren to reduce transmission of S. haematobium and S. mansoni.
Justin Komguep Nono, Justin Komguep Nono, Justin Komguep Nono, Justin Komguep Nono, Severin Donald Kamdem, Severin Donald Kamdem, Severin Donald Kamdem, Palmer Masumbe Netongo, Smritee Dabee, Michael Schomaker, Alim Oumarou, Frank Brombacher, Frank Brombacher, Frank Brombacher, Frank Brombacher, Roger Moyou-Somo   +15 more
doaj   +1 more source

Great minds map alike: Citizen and expert distribution models of schistosome snail hosts in rural west Uganda

Ecological Solutions and Evidence, Volume 6, Issue 4, October–December 2025.
Citizen scientists and an expert jointly monitor Biomphalaria snails (the intermediate host of Schistosoma mansoni) in rural areas of southwest Uganda, generating over 4500 georeferenced records. By comparing expert‐ and citizen‐based distribution models under perfect and imperfect detection, we demonstrate that site type and NDVI consistently ...
Noelia Valderrama‐Bhraunxs, Tine Huyse, Emiel van Loon, Anton Van Rompaey, Ronald Twongyirwe, Liesbet Jacobs   +5 more
wiley   +1 more source

Bayesian risk mapping and model-based estimation of Schistosoma haematobium-Schistosoma mansoni co-distribution in Côte d'Ivoire.

PLoS Neglected Tropical Diseases, 2014
BackgroundSchistosoma haematobium and Schistosoma mansoni are blood flukes that cause urogenital and intestinal schistosomiasis, respectively. In Côte d'Ivoire, both species are endemic and control efforts are being scaled up.
Frédérique Chammartin, Clarisse A Houngbedji, Eveline Hürlimann, Richard B Yapi, Kigbafori D Silué, Gotianwa Soro, Ferdinand N Kouamé, Eliézer K N Goran, Jürg Utzinger, Giovanna Raso, Penelope Vounatsou   +10 more
doaj   +1 more source