The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni [PDF]
Memorias do Instituto Oswaldo Cruz, 2019 BACKGROUND Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease.
Gilmara Lima Nascimento +6 more
doaj +3 more sources
Sensitivity and Specificity of Multiple Kato-Katz Thick Smears and a Circulating Cathodic Antigen Test for Schistosoma mansoni Diagnosis Pre- and Post-repeated-Praziquantel Treatment [PDF]
PLoS Neglected Tropical Diseases, 2014 Two Kato-Katz thick smears (Kato-Katzs) from a single stool are currently recommended for diagnosing Schistosoma mansoni infections to map areas for intervention. This ‘gold standard’ has low sensitivity at low infection intensities.
A Koukounari +56 more
core +31 more sources
Schistosomiasis Mansoni-Recruited Eosinophils: An Overview in the Granuloma Context. [PDF]
Microorganisms, 2022 Eosinophils are remarkably recruited during schistosomiasis mansoni, one of the most common parasitic diseases worldwide. These cells actively migrate and accumulate at sites of granulomatous inflammation termed granulomas, the main pathological feature ...
Malta KK +5 more
europepmc +2 more sources
Rutin, a Flavonoid Compound Derived from Garlic, as a Potential Immunomodulatory and Anti-Inflammatory Agent against Murine Schistosomiasis mansoni. [PDF]
Nutrients, 2023 Schistosomiasis is a tropical disease caused by trematode worms. The inflammatory response of the host to schistosome eggs leads to formation of granuloma in the liver and intestine. Praziquantel (PZQ) is still an effective treatment for schistosomiasis,
Hamad RS.
europepmc +2 more sources
Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni. [PDF]
PLoS Neglected Tropical Diseases, 2016 Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated.
Thiago Almeida Pereira +13 more
doaj +2 more sources
Arquivos de Gastroenterologia, 2014 Context Studies have described the correlation between platelet count and the stages of fibrosis in chronic viral hepatitis, but few publications have studied this correlation in Schistosomiasis mansoni.
Tibério B MEDEIROS +3 more
doaj +2 more sources
PLoS ONE, 2015 Miltefosine (MFS) is an alkylphosphocholine used for the local treatment of cutaneous metastases of breast cancer and oral therapy of visceral leishmaniasis.
Maha M. Eissa +5 more
openalex +3 more sources
Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation. [PDF]
PLoS ONE, 2013 The aim of this study is to investigate renal markers and the biomarker MCP-1 in patients with schistosomiasis mansoni. This is a cross-sectional study with 85 patients aged 5 to 48 years, with a confirmed diagnosis of schistosomiasis mansoni through the
Ana Lúcia P Hanemann +6 more
doaj +2 more sources
Human Plasma Lipid Modulation in Schistosomiasis Mansoni Depends on Apolipoprotein E Polymorphism
PLoS ONE, 2014 Background Schistosomiasis mansoni is a parasitic liver disease, which causes several metabolic disturbances. Here, we evaluate the influence of Apolipoprotein E (APOE) gene polymorphism, a known modulator of lipid metabolism, on plasma lipid levels in ...
Caíque Silveira Martins da Fonseca +6 more
openalex +3 more sources
A survey of the prevalence of Schistosomiasis among pupils in Apata and Laranto areas in Jos, Plateau State [PDF]
Online Journal of Health & Allied Sciences, 2004 Prevalence of Schistosomiasis in apparently healthy primary school pupils in Apata and Laranto areas of Jos was surveyed using 300 samples of stool and 300 samples of urine.
Okpala HO +5 more
doaj +1 more source