One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo+135 more
core +4 more sources
Schistosomiasis is a neglected tropical disease (NTD) caused by infection with parasitic trematodes of the genus Schistosoma that can lead to debilitating morbidity and mortality.
John Archer+17 more
doaj +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier+26 more
wiley +1 more source
Development of novel multiplex microsatellite polymerase chain reactions to enable high-throughput population genetic studies of Schistosoma haematobium [PDF]
© 2015 Webster et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
A. A. Hamidou+23 more
core +4 more sources
ABSTRACT Background Esophageal varices (EV) are a fatal complication of cirrhosis. The guidelines suggest that esophageal varices should be diagnosed before bleeding in all patients. In patients with cirrhosis, the Child Turcotte Pugh (CTP) class has been used as a prognostic tool for variceal bleeding.
Eltype Elsiddig+3 more
wiley +1 more source
Decline in transmission of schistosomiasis mansoni in Oman
Intestinal schistosomiasis due to Schistosoma mansoni was first reported in Oman in 1979. We describe the trend in parasitological and serological prevalence of human infection with S. mansoni in the endemic area over the period 1982-2014, and the compliance of data generated by the national monitoring and evaluation system with schistosomiasis ...
Idris Al Abaidani+7 more
openaire +3 more sources
: INTRODUCTION Risk of schistosomiasis expansion to semi-arid northeastern Brazil under the influence of the Integration Project of the São Francisco River (IPSFR) was assessed.
Tereza Cristina Favre+5 more
doaj +1 more source
Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs
The skin functions as both a protective barrier and an autonomous immune organ, maintaining dynamic interactions with internal organs. This review analyzes skin‐organ crosstalk mechanisms, highlighting key cytokines (particularly IL‐17A) and microbial metabolites that mediate interorgan communication.
Wende Deng+7 more
wiley +1 more source
Diagnosis of \u3cem\u3eSchistosoma mansoni\u3c/em\u3e without the Stool: Comparison of Three Diagnostic Tests to Detect \u3cem\u3eSchiostosoma mansoni\u3c/em\u3e Infection from Filtered Urine in Zambia [PDF]
Diagnosis for intestinal Schistosoma mansoni lacks sensitivity and is arduous to conduct. The standard diagnostic tests, Kato-Katz (KK) and circulating cathodic antigen (CCA) both lack sensitivity and with KK, require obtaining, transporting, and ...
Lodh, Nilanjan+3 more
core +1 more source
Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE+22 more
core +2 more sources