Results 51 to 60 of about 12,926 (209)

Critical Role of Skin in Pathogenesis: Bidirectional Crosstalk Between Skin and Multiple Organs

MedComm – Future Medicine, Volume 4, Issue 2, June 2025.
The skin functions as both a protective barrier and an autonomous immune organ, maintaining dynamic interactions with internal organs. This review analyzes skin‐organ crosstalk mechanisms, highlighting key cytokines (particularly IL‐17A) and microbial metabolites that mediate interorgan communication.
Wende Deng, Junyi Liu, Changheng Tang, Zhenghao Li, Ying Qiu, Han Zhou, Lanxuan Yang, Ting Li   +7 more
wiley   +1 more source

Treatment of Schistosomiasis mansoni with Neostibosan.

Experimental Biology and Medicine, 1946
Twelve patients with ova of 5. mansoni in their stools were treated with the pentavalent antimonial drug, neostibosan (Winthrop). The patients were all males with ages ranging from 15 to 32 years. The drug was administered intravenously during a 2-week period of hospitalization.
Federico Hernandez-Morales, Caroline K. Pratt, José Oliver-González   +2 more
openaire   +3 more sources

Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Schistosomiasis, a neglected tropical disease infecting over 200 million people globally, has limited therapeutic options. The 20S proteasome is a validated drug target for many parasitic infections, including those caused by Plasmodium and Leishmania, and we have previously demonstrated antischistosomal activity with inhibitors targeting ...
Elany B. Silva, Zhenze Jiang, Chenxi Liu, Pavla Fajtová, Thaiz R. Teixeira, Giovana de Castro Fiorini Maia, Lawrence J. Liu, Nelly El‐Sakkary, Danielle E. Skinner, Ali Syed, Steven C Wang, Conor R. Caffrey, Anthony J. O'Donoghue   +12 more
wiley   +1 more source

Temperature and Resources Interact to Affect Transmission via Host Foraging Rate and Susceptibility

Ecology Letters, Volume 28, Issue 6, June 2025.
Environmental conditions such as temperature and resource availability can shape disease transmission by altering contact rates and/or the probability of infection given contact. We develop mechanistic models and fit them to experimental data to uncover how temperature and resources jointly affect transmission of fungal parasites (Metschnikowia ...
Daniel C. Suh, Katie Schroeder, Alexander T. Strauss   +2 more
wiley   +1 more source

Schistosoma mansoni: a rare cause of tubal infection

Brazilian Journal of Infectious Diseases, 2010
S. haematobium is an important cause of urinary schistosomiasis, and symptomatic female genital infection is a common gynecological finding in areas where S. haematobium is prevalent.
C.A. Faria, J.C.J. Conceição, T.F. Valadares, B. Rodrigues, L. Carneiro   +4 more
doaj  

Assessment of schistosomiasis in the semi-arid Northeast region of Brazil: the São Francisco River large-scale water transposition project

Revista da Sociedade Brasileira de Medicina Tropical, 2016
: INTRODUCTION Risk of schistosomiasis expansion to semi-arid northeastern Brazil under the influence of the Integration Project of the São Francisco River (IPSFR) was assessed.
Tereza Cristina Favre, Monica Ammon Fernandez, Lilian Christina Nóbrega Holsbach Beck, Ricardo José de Paula Souza Guimarães, Otávio Sarmento Pieri, Silvana Aparecida Carvalho Thiengo   +5 more
doaj   +1 more source

Co‐endemicity of schistosomiasis and tegumentary leishmaniasis: Spatial co‐clustering in endemic areas

Tropical Medicine &International Health, Volume 30, Issue 6, Page 556-568, June 2025.
Abstract Objectives Schistosomiasis and tegumentary leishmaniasis simultaneously affect areas in tropical and subtropical regions. Co‐infected individuals show a less‐than‐optimal response to treatment and increased regulatory immune responses. However, no study has determined where Schistosoma–Leishmania co‐infections are more likely to occur ...
Genil Mororó Araújo Camelo, Jeferson Kelvin Alves de Oliveira Silva, Dharliton Soares Gomes, Laura Maggi, Stefan Michael Geiger, David Soeiro Barbosa, Deborah Aparecida Negrão‐Corrêa   +6 more
wiley   +1 more source

Decline in transmission of schistosomiasis mansoni in Oman

Infectious Diseases of Poverty, 2016
Intestinal schistosomiasis due to Schistosoma mansoni was first reported in Oman in 1979. We describe the trend in parasitological and serological prevalence of human infection with S. mansoni in the endemic area over the period 1982-2014, and the compliance of data generated by the national monitoring and evaluation system with schistosomiasis ...
Idris Al Abaidani, Seif Al-Abri, Mahmoud Shaban, Satish L. Ghugey, Salem Al Kathery, Khalid Al-Mashikhi, Amadou Garba, Albis Francesco Gabrielli   +7 more
openaire   +3 more sources

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, Volume 6, Issue 5, May 2025.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Characteristics of Intestinal Flora in Patients With Schistosoma japonicum Infection Undergoing Splenectomy

Parasite Immunology, Volume 47, Issue 5, May 2025.
ABSTRACT Schistosomiasis japonica is a parasitic disease that seriously endangers human health. Patients with advanced Schistosoma japonicum infection often suffer from cirrhosis and portal hypertension. Splenectomy has been widely used in the treatment of these patients. Previous studies have confirmed that S. japonicum infection is closely related to
Chen Zhou, Pengpeng Zhang, Yingzi Ming
wiley   +1 more source