Results 121 to 130 of about 495 (168)

Structure and Activity of Thiazole-Type Schistosomicidal Agents

Journal of Pharmaceutical Sciences, 1972
The schistosomicidal agent 1-(5′-nitro-2′-thiazolyl)-2-imidazolidinone caused a rise in the α-keto acid level when given orally to rats. This effect could be diminished upon parallel administration of high doses of the vitamin thiamine. The biological effect of the drug could also be canceled through similar administration of the vitamin.
I, Nabih, F, el-Hawary, H, Zoorob
openaire   +2 more sources

Synthesis of Substituted Benzthiaxanthones for Possible Schistosomicidal Activity

Journal of Pharmaceutical Sciences, 1974
New substituted benzthiaxanthones were synthesized in an attempt to find new compounds that may have schistosomicidal activity.
I, Nabih, A, Zayed
openaire   +2 more sources

Thermoanalytical characterization of potentially schistosomicide polymeric derivatives

Journal of Thermal Analysis and Calorimetry, 2004
Oxamniquine (OXA) is a schistosomicide agent that causes some adverse effects in central nervous system. Intending to improve OXA therapeutic properties, a polymeric prodrug was designed. Currently, there is an increasing interest of thermal analytical techniques in the pharmaceutical area, so differential thermal analysis (DTA) and thermogravimetry ...
R. Parise Filho, A. A. S. Araújo, M. Santos Filho, J. R. Matos, M. A. B. Silveira, C. A. Brandt   +5 more
openaire   +1 more source

The chemistry of schistosomicides.

Egyptian journal of bilharziasis, 1977
The chemistry of the different compounds applied in the field of schistosomicides has been reviewed in detail. On the basis of their chemical constitution, these compounds have been classified into: organotrivalent antimonials; Xanthones and related compounds "xanthones, chromones and mirasans"; Nitroheterocyclic compounds "nitroquinolines, nitrofurans
openaire   +1 more source

BIOCHEMICAL EFFECTS OF SCHISTOSOMICIDES*

Annals of the New York Academy of Sciences, 1969
E, Bueding, J, Fisher
openaire   +2 more sources

Schistosomicidal 5-nitro-4-thiazolines

Journal of Medicinal Chemistry, 1972
Peter J. Islip, Michael D. Closier, Martin C. Neville, Leslie M. Werbel, David B. Capps   +4 more
openaire   +2 more sources

New furoxan derivatives with Schistosomicidal activity.

2014
Schistosomiasis is a chronic inflammatory disease caused by trematode flatworms of the genus Schistosoma. The disease remains a major neglected, poverty-related disease in many tropical areas. Praziquantel is currently the only drug administrated to treat schistosomiasis; as praziquantel-resistant worms have been found it is an urgent need to find new ...
CORTESE, DANIELA, David L. Williams, Peter D. Ziniel, Latasha Day, GUGLIELMO, Stefano, FRUTTERO, Roberta, Alberto Gasco   +6 more
openaire   +1 more source

Synthetic schistosomicides. XVIII. N-(4-[[2-(Diethylamino)ethyl]amino]-1-naphthyl)amides, N-[5,6,7,8-tetrahydro-4-[(3-piperidinopropyl)amino]-1-naphthyl]amides, and related amide and urea derivatives

, 1970
Leslie M. Werbel, Josephine Battaglia, Edward F. Elslager, C. YOUNGSTROM   +3 more
openalex   +1 more source

The association of steroids and schistosomicides in the treatment of experimental schistosomiasis

, 1989
José Roberto Lambertucci, J. Modha, R. Curtis, Michael J. Doenhoff   +3 more
openalex   +1 more source

ChemInform Abstract: NEUE SCHISTOSOMICIDE UND CARCINOSTATISCHE MITTEL VOM TYP THIAXANTHON

, 1972
I. Nabih, A. ZAYED
openalex   +1 more source