Results 181 to 190 of about 1,025,722 (378)
Intepirdine Derivatives Possessing Dual 5HT6 Antagonism / HDAC6 Inhibitory Activity
Chemistry – A European Journal, EarlyView.In the context of developing therapies for dementias and cognitive decline, potent dual acting molecules targeting the GPCR 5HT6 and the enzyme HDAC6 with favorable BBB penetration profile were designed and synthesised. Abstract Alzheimer's Disease (AD) impacts significantly the quality of life of people aged over 65 years old, while millions more ...
Andreas Gkanas +9 more
wiley +1 more source
Clinical Observations with Frenquel in Chronic Schizophrenia [PDF]
, 1956 O. Lindan, C. H. Cahn, H. E. Lehmann
openalex +1 more source
A PSYCHOLINGUISTIC ANALYSIS OF SCHIZOPHRENIC SPEECH REFLECTING HALLUCINATION AND DELUSION IN THE CAVEMAN’S VALENTINE [PDF]
, 2012 The objectives of this research are (1) to explain the speech abnormalities of a schizophrenic character, Romulus, in The Caveman’s Valentine; and (2) to present the characteristics of schizophrenia represented by Romulus in his speech.
NARISWARI, PINDHANINGTYAS
core
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
ChemMedChem, Accepted Article.Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti +4 more
wiley +1 more source
Psycho-galvanic Studies in Schizophrenia. (Arch. of Neur. and Psychiat., December, 1926.) Syz, H. C. [PDF]
, 1927 G. W. T. H. Fleming
openalex +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Aripiprazole once‐monthly (AOM) is approved for the maintenance monotherapy treatment of bipolar I disorder (BP‐I) in adults. A previously developed population pharmacokinetic model was validated by applying it to data from patients diagnosed with BP‐I.
Xiaofeng Wang +10 more
wiley +1 more source
Schizophrenia and Cerebral Tumour. (Ann. Méd. Psych., January, 1931) Claude, H., and Baruk, H. [PDF]
, 1932 S. M. Coleman
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Clinical Pharmacology &Therapeutics, EarlyView.CYP2D6 alleles with low frequency in Eurocentrically biased study populations are often excluded from pharmacogenetic investigation and consequently may have misassigned activity values. This health inequity may be contributing to imprecise dose predictions for CYP2D6‐metabolizing drugs.
Oyinlade Kehinde +6 more
wiley +1 more source