Results 171 to 180 of about 693,765 (295)

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

iNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang, Linbo Xie, Mengdan Chen, Yi Ji, Yibing Yan, Shanshan Zhou, Panpan Hu, Xingqi Wu, Kai Wang   +8 more
wiley   +1 more source

Alexithymia in Schizophrenia and Psychosis Vulnerability: A Systematic Review and Meta‐Analysis

Journal of Clinical Psychology, Volume 81, Issue 6, Page 410-424, June 2025.
ABSTRACT Aims Disturbances involving impairments in experience and expression of affect are frequently identified in schizophrenia samples. Alexithymia underlies cognitive impairments in identification and expression of affect, further implicated in affect dysregulation.
Ercan Ozdemir, Zhuoni Xiao, Helen Griffiths, Angus MacBeth   +3 more
wiley   +1 more source

Clinical dilemma of mood stabilizer augmentation in treatment-resistant schizophrenia with residual phase: A case report of valproate-associated hypoglycemia and cytopenia, and subsequent lithium response. [PDF]

PCN Rep
Kasagi Y, Okamoto N, Yoshimura R.
europepmc   +1 more source

Differences in patterns of attention deficit/hyperactivity disorder medication use in US children

JCPP Advances, EarlyView.
Abstract Background Understanding attention deficit/hyperactivity disorder (ADHD) medication patterns is crucial for optimizing treatment outcomes. There are limited data on racial, ethnic, gender and socioeconomic treatment differences across longitudinal national samples.
Jennie E. Ryan, Alexander Weigard, Sean Esteban McCabe, Timothy E. Wilens, Philip T. Veliz   +4 more
wiley   +1 more source

Psychopathy traits and their link to emotion recognition impairments in conduct disorder

JCPP Advances, EarlyView.
Abstract Background Neurocognitive models suggest that callous‐unemotional (CU) traits in youths with conduct disorder (CD) are linked to emotion recognition impairments, particularly in identifying distress emotions like fear and sadness. However, CD may be accompanied by grandiose‐manipulative (GM) and/or impulsive‐irresponsible (II) traits in ...
Gregor Kohls, Anka Bernhard, Graeme Fairchild, Christina Stadler, Lucres Jansen, Stephane A. De Brito, Veit Roessner, Christine M. Freitag, Kerstin Konrad, Erik M. Elster   +9 more
wiley   +1 more source

Neural correlates of resilience to trauma during adolescence: A multi‐modal study

JCPP Advances, EarlyView.
Abstract Background Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting‐state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms ...
Lu Zhang, Vanessa L. Cropley, Divyangana Rakesh, Sarah Whittle   +3 more
wiley   +1 more source

Genetic evidence for causal relationship between general cognition and treatment resistance in schizophrenia. [PDF]

Transl Psychiatry
Li C, Zhong Y, Sham PC, Chan SKW.
europepmc   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

JCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan, Robbie Duschinsky, Marian J. Bakermans‐Kranenburg, Lianne Bakkum, Guy C. M. Skinner, Alfred Markham, Helen Beckwith, Marinus H. van Ijzendoorn   +7 more
wiley   +1 more source

Autism spectrum disorder and co-occurring schizophrenia. [PDF]

CMAJ
Phung N, Greben R, Fernandes N, Chopra N.   +3 more
europepmc   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

JCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave, Marthe de Roo, Charlotte Vrijen, Tina Kretschmer   +3 more
wiley   +1 more source