Results 151 to 160 of about 260,883 (251)

Antipsychotic discontinuation in schizophrenia: rational or reckless?

Schizophrenia
Robert B. Zipursky, Ofer Agid, Gary Remington   +2 more
doaj   +1 more source

Prevalence, adherence, and health care resource utilization in schizophrenia: A national and state-level analysis of US Medicaid Beneficiaries. [PDF]

J Manag Care Spec Pharm
Parks J, Xiang P, Patel R, McBride K, Costantino H, Mirza S, Borsos K.   +6 more
europepmc   +1 more source

The role of rare copy number variants in early‐onset depression

JCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison, Ida Sønderby, Miguel Garcia‐Argibay, Victoria Powell, Amy Shakeshaft, Lucy Riglin, Elliott Rees, Michael O’Donovan, Henrik Larsson, Ole Andreassen, Alexandra Havdahl, Joanna Martin, Anita Thapar   +12 more
wiley   +1 more source

Balancing one's own life with caregiving for a sibling with schizophrenia: A qualitative study. [PDF]

Int J Nurs Stud Adv
Kawaguchi M, Katayama M, Nakamoto A, Morioka H, Kawamura M.   +4 more
europepmc   +1 more source

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

Decision processes in 3D structural MRI schizophrenia classification evaluated with saliency maps. [PDF]

Sci Rep
Jelitzki J, Reichenbach A, Windberger A.
europepmc   +1 more source

Disentangling shared and unique effects of parenting on psychopathology: Evidence from two prospective, genetically sensitive cohort studies

JCPP Advances, EarlyView.
Abstract Background Multiple dimensions of parenting–including hostility, conflict, and warmth–are associated with an array of mental disorders in youth. We tested two possible explanations for these associations: Parenting may shape a shared liability to experience many forms of psychopathology (“shared‐liability” hypothesis), or parenting may shape ...
Leah S. Richmond‐Rakerd, Lara Khalifeh, S. Alexandra Burt, Jody M. Ganiban, Rachel E. Hsu, Luke W. Hyde, Sujin Lee, Leslie D. Leve, Misaki N. Natsuaki, Jenae M. Neiderhiser, David Reiss, Daniel S. Shaw, Gabriela L. Suarez, Jasmin Wertz   +13 more
wiley   +1 more source

The dysconnection hypothesis of schizophrenia: a 30-year update. [PDF]

World Psychiatry
Friston K.
europepmc   +1 more source

Alterations in resting‐state functional connectivity relate to psychopathology trajectories during emerging adolescence

JCPP Advances, EarlyView.
Abstract Background A general psychopathology “p‐factor” captures shared variation across psychiatric disorder categories and is associated with dysfunctions in cognitive control. Alterations in resting‐state functional connectivity (RSFC) of cognitive and attentional networks have been associated concurrently with the p‐factor in youth samples ...
Jenna Jones Devine, Garrett R. Hosterman, Jolee Sloss, Adrienne L. Romer   +3 more
wiley   +1 more source

Relaxation of Japan's clozapine monitoring system is urgently needed: Adding 10,000 future prescriptions may prevent up to 400 schizophrenia-related suicides and cost 1 death by agranulocytosis. [PDF]

PCN Rep
de Leon J, Kikuchi Y, Yasui-Furukori N.
europepmc   +1 more source