Results 41 to 50 of about 29,756 (180)

Population genomics of the fission yeast Schizosaccharomyces pombe. [PDF]

open access: yesPLoS ONE, 2014
The fission yeast Schizosaccharomyces pombe has been widely used as a model eukaryote to study a diverse range of biological processes. However, population genetic studies of this species have been limited to date, and we know very little about the ...
Jeffrey A Fawcett   +10 more
doaj   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

open access: yesCytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

Incidence oenologique du traitement biologique de la vigne par Trichoderma viride a l'egard de la pourriture grise

open access: yesOENO One, 1982
T. viride actif contre B. cinerea et d'autres champignons parasites de la vigne (A. carneus, P. frequentans, P. roqueforti) ne modifie ni la composition du moût ni sa couleur; il ne présente aucune action inhibitrice sur S.
B. S. Găină   +2 more
doaj   +1 more source

Optimisation of the Schizosaccharomyces pombe urg1 expression system. [PDF]

open access: yesPLoS ONE, 2013
The ability to study protein function in vivo often relies on systems that regulate the presence and absence of the protein of interest. Two limitations for previously described transcriptional control systems that are used to regulate protein expression
Adam T Watson   +6 more
doaj   +1 more source

Transposons as Tools for Future Genome Engineering in Yeasts and Filamentous Fungi

open access: yesYeast, EarlyView.
Applications of transposon‐based tools for genome engineering in fungi include transposon‐mediated mutagenesis and targeted genomic integration. ABSTRACT Transposons are fundamental genetic elements that have profoundly shaped the architecture of eukaryotic genomes.
Bingyin Peng   +4 more
wiley   +1 more source

Systematic analysis reveals the prevalence and principles of bypassable gene essentiality

open access: yesNature Communications, 2019
An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential ...
Jun Li   +10 more
doaj   +1 more source

Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe

open access: yesLife Science Alliance, 2022
Characterization of nuclear pores in Schizosaccharomyces pombe identifies regions of heterogeneous NPC density and composition and shows that NPCs are excluded near the spindle pole body by Lem2-mediated centromere tethering.
Joseph M Varberg   +4 more
doaj   +1 more source

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

open access: yesThe FEBS Journal, EarlyView.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar   +3 more
wiley   +1 more source

HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evidence
Zsigmond Benko   +4 more
doaj   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

open access: yesThe FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao   +3 more
wiley   +1 more source

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