Results 141 to 150 of about 74,140 (300)

Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast

mBio
Inositol pyrophosphates 5-IP7, 1-IP7, and 1,5-IP8 are eukaryal signaling molecules that influence cell physiology, especially phosphate homeostasis. In fission yeast, 1,5-IP8 and 1-IP7 impact gene expression by acting as agonists of RNA 3'-processing and
Beate Schwer, Isabel Prucker, Ana M. Sanchez, Jill Babor, Henning J. Jessen, Stewart Shuman   +5 more
doaj   +1 more source

Engineering ER-stress dependent non-conventional mRNA splicing

eLife, 2018
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Meghan Zubradt, Jonathan S Weissman, Peter Walter   +6 more
doaj   +1 more source

Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe [PDF]

, 2010
Nonsense-mediated mRNA decay (NMD) is a translation-linked process that destroys mRNAs with premature translation termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, usually PTCs trigger strong NMD only when positioned
Carter MS, Culbertson MR, Hodgkin J, Jikai Wen, Le Hir H, Muhlemann O, Peltz SW, Saverio Brogna, Zhang J, Zhang SA   +9 more
core   +3 more sources

A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity

G3: Genes, Genomes, Genetics, 2011
The fission yeast Schizosaccharomyces pombe has been widely used to study eukaryotic cell biology, but almost all of this work has used derivatives of a single strain. We have studied 81 independent natural isolates and 3 designated laboratory strains of
W. Brown, Gianni Liti, C. Rosa, S. James, I. Roberts, V. Robert, N. Jolly, Wen Tang, P. Baumann, Carter Green, Kristina Schlegel, Jonathan Young, Fabienne Hirchaud, S. Leek, Geraint Thomas, A. Blomberg, J. Warringer   +16 more
semanticscholar   +1 more source

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

PLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong, Hyeonseok Jin, Jeong Ho Chang   +2 more
doaj   +1 more source

New Scaling Relation for Information Transfer in Biological Networks [PDF]

arXiv, 2015
Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems. To address this question, we provide a rigorous case study of the informational architecture of two representative biological networks: the ...
arxiv  

Phytochelatin Synthase Genes from Arabidopsis and the Yeast Schizosaccharomyces pombe

, 1999
Phytochelatins (PCs), a family of heavy metal–inducible peptides important in the detoxification of heavy metals, have been identified in plants and some microorganisms, including Schizosaccharomyces pombe , but not in animals.
S. Ha, Aaron P. Smith, R. Howden, Wendy Dietrich, S. Bugg, M. O’Connell, P. Goldsbrough, C. Cobbett   +7 more
semanticscholar   +1 more source

TORC1-Dependent Phosphorylation Targets in Fission Yeast

Biomolecules, 2017
Target of rapamycin (TOR) kinase controls cell metabolism and growth in response to environmental cues such as nutrients, growth factors, and stress. TOR kinase is widely conserved across eukaryotes.
Yoko Otsubo, Akio Nakashima, Masayuki Yamamoto, Akira Yamashita   +3 more
doaj   +1 more source

Correlating yeast cell stress physiology to changes in the cell surface morphology:atomic force microscopic studies [PDF]

, 2006
Yeasts are unicellular haploid fungi that help us to bake bread and ferment alcoholic beverages, but in some cases, they can cause infections that are sometimes fatal.
Adya, Ashok K., Canetta, Elisabetta, Walker, Graeme M.   +2 more
core   +2 more sources

Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe [PDF]

, 1991
The rad9.192 DNA repair mutant from the fission yeast, Schizosaccharomyces pombe, is sensitive to both UV and ionising radiation. The rad9 gene has been cloned by complementation of the gamma-ray sensitivity of the mutant cell line.
Carr, Antony M, Lehmann, Alan R, Murray, Johanne M, Watts, Felicity Z   +3 more
core   +2 more sources