Results 101 to 110 of about 989,611 (332)

Micro Elastofluidics for Tuneable Droplet Merging

Advanced Materials Technologies, EarlyView.
This technical paper provides a proof of concept of fully flexible and stretchable microfluidic technology for tuneable droplet mixing and merging. The phenomenon is justified through theoretical, numerical and experimental studies. ABSTRACT Droplet microfluidics enables precise handling of discrete fluid volumes at the microscale, with broad ...
Uditha Roshan, Amith Mudugamuwa, Xiaoyue Kang, Prabuddha De Saram, Fariba Malekpour Galogahi, Du Tuan Tran, Lingxi Ouyang, Jun Zhang, Nam‐Trung Nguyen   +8 more
wiley   +1 more source

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Recycling bins, garbage cans or think tanks? Three myths regarding policy analysis institutes [PDF]

, 2007
The phrase 'think tank' has become ubiquitous – overworked and underspecified – in the political lexicon. It is entrenched in scholarly discussions of public policy as well as in the 'policy wonk' of journalists, lobbyists and spin-doctors. This does not
Abelson D, Andjelkovic B, Bakvis H, Boas M., Boucher S., Denham A., DIANE STONE, Hajer M., Halfmann W., Ionita S, Keohane R.O., Kingdon J, Krause Hansen H., Ladi S, McGann J., Miller C., Minggiu-Pippidi A, Overseas Development Council (ODC), Palley T, Reinicke W, Saint-Martin D, Shinn J., Smith J.A, Stone D, Struyk R.J, UNDP (United Nations Development Program), Weaver R. Kent   +26 more
core   +1 more source

Introduction [PDF]

, 2018
In recent years, increasing attention has been devoted to the underrepresentation, exclusion or outright discrimination experienced by women and members of other visible minority groups in academic philosophy. Much of this debate has focused on the state
Contesi, Filippo, Terrone, Enrico
core  

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Competition and cooperation: Libraries and publishers in the transition to electronic scholarly journals

, 1999
The conversion of scholarly journals to digital format is proceeding rapidly, especially for those from large commercial and learned society publishers. This conversion offers the best hope for survival for such publishers.
Odlyzko, Andrew
core   +2 more sources

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Another Workflow Is Possible: Building Trust and Relinquishing Control for Multilingual Digital Publishing Futures

Journal of Electronic Publishing
How can we build new multilingual futures for academic journals in the age of electronic publishing? The answer may lie in the multilingual pasts of scholarly publishing.
Roopika Risam
doaj   +2 more sources