Results 131 to 140 of about 989,611 (332)

A Proposed Solution to the Scholarly Communication Crisis

, 2007
After reviewing the history and parameters of the scholarly communications crisis, particularly in regard to skyrocketing prices for journals in the natural sciences, the author reviews and rejects previously attempted solutions.
Schatzle, Chad J.
core  

Writing In and Around Video Games [PDF]

, 2015
This undergraduate course uses video games as a lens through which to explore the infinitely broader topic of digital rhetoric. Students encounter games in several different ways: as texts to analyze, raw material for video compositions, systems to ...
Sierra, Wendi
core   +1 more source

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

Advanced Science, EarlyView.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang, Shan Guo, Yu Zhang, He Ren, Ke Lei, Chenyang Zhao, Qian Yu, Hongqing Luo, Yujing Xiao, Xiaoming Feng, Xiaoyu Li   +10 more
wiley   +1 more source

The Genetic Dossier in the Web of Data

magazén
While archivists and genetic scholars differ considerably in their methodological frameworks, the digital turn in archival preservation and scholarly editing provides an opportunity to narrow the gap.
Pereira, Elsa
doaj   +1 more source

The scholarly data edition

In the last decade, big textual datasets in the humanities have become increasingly more available in the form of raw data. The challenges these datasets raise are twofold. On the one hand, most humanities scholars are not equipped with skills in text and data mining. This remains a barrier to study big data in the humanities.
openaire   +1 more source

Textual criticism [PDF]

, 2005
Gabler, Hans Walter, Groden, Michael
core   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source

Assumptions Fruitfully Disturbed [PDF]

, 1989
Gabler, Hans Walter
core   +1 more source

Advanced Multiscale Modeling for Revealing Anomalous Fluid Transport Induced by Confinement Interfacial Layer Reconstruction in Sub‐10 nm Space

Advanced Science, EarlyView.
Integrating experimental insights with molecular dynamics simulations, we establish an advanced mathematical model for fluids confined in sub‐10‐nm channels, enabling quantitative prediction of interfacial layer thickness and viscosity by accounting for channel material, temperature, and fluid properties.
Xiang Zhang, Bing Wei, Jingyi Wang, Runnan Wu   +3 more
wiley   +1 more source