Results 41 to 50 of about 19,796 (265)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

Human heritable genome editing and its governance: views of scientists and governance professionals

New Genetics and Society
Heritable human genome editing has garnered significant attention in scholarly and lay media, yet questions remain about whether, when, and how heritable genome editing ought to proceed.
R. Jean Cadigan, Margaret Waltz, John M. Conley, Rami M. Major, Elizabeth K. Branch, Eric T. Juengst, Michael A. Flatt   +6 more
doaj   +1 more source

TEI and Project Bamboo

Journal of the Text Encoding Initiative, 2013
Project Bamboo, a cyberinfrastructure initiative supported by the Andrew W. Mellon Foundation, takes as its core mission the enhancement of arts and humanities research through the development of shared technology services.
Quinn Dombrowski, Seth Denbo
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

Advanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan, Lei Wu, Dong Zhang, Linxiao Wu, Graca Ferreira Vaz Pinto Mendes, Wanqiao J. Tu, Heping Ma, Toby J. Proctor, Colin R. Butler, Thomas Kjærgaard, Mark W. Lowdell, Martin A. Birchall, Robert E. Hynds, Richard Hewitt, Wenhui Song   +14 more
wiley   +1 more source

The future of the digital scholarly editor: interpretation, subjectivity and presence?

Manuscrítica, 2015
The technological innovations, and the possibilities that come with them, have far-reaching implications for the activity of a scholarly editor. Digital technologies can facilitate or even replace several traditional tasks of scholarly editing and ...
Elli Bleeker
doaj  

Electronic Scholarly Editing in the University Classroom: an Approach to Project-based Learning

Digital Studies, 2012
This paper describes a project-based senior undergraduate course in electronic scholarly editing at the University of Saskatchewan. Students used HTML to prepare and publish on the World Wide Web electronic documentary editions of two seventeenth-century
Allison Muri, Joel E. Salt, Ronald Wayne Cooley   +2 more
doaj   +1 more source

Recensione: Mancinelli, Tiziana, e Elena Pierazzo. 2020. Che cos’è un’edizione scientifica digitale. Roma: Carocci

Umanistica Digitale, 2020
This paper offers a review to Mancinelli, Tiziana, e Elena Pierazzo. 2020. Che cos’è un’edizione scientifica digitale. Roma: Carocci (Bussole), pp. 125, ISBN: 978-8843099054.
Anna Cappellotto
doaj   +1 more source

Digital Scholarly Editions Manifesto

Umanistica Digitale, 2022
Italian translation of the Manifest für digitale ...
Fabio Ciotti, Elena Corradini, Elisa Cugliana, Giulia D'Agostino, Lorenzo Ferroni, Franz Fischer, Maurizio Lana, Paolo Monella, Torsten Roeder, Roberto Rosselli Del Turco, Patrick Sahle   +10 more
openaire   +1 more source