Results 61 to 70 of about 1,061,484 (325)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Visibility of latin american scientific publications: the example of Bolivia (Portuguese original version) [PDF]

open access: yesJCOM: Journal of Science Communication, 2006
The discussion on the state of the art of scientific publications in Latin American countries generally restricts itself to its supposedly low visibility.
Silvia Cristina Pabón Escobar   +1 more
doaj  

Ten Hot Topics around Scholarly Publishing

open access: yesPubl., 2019
The changing world of scholarly communication and the emerging new wave of ‘Open Science’ or ‘Open Research’ has brought to light a number of controversial and hotly debated topics.
Jonathan P. Tennant   +15 more
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

WAYS TO IMPROVE VISIBILITY OF PUBLICATIONS

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics, 2021
WAYS TO IMPROVE VISIBILITY OF ...
Ilke Coskun Benlidayi
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

The role of learned societies in national scholarly publishing

open access: yesLearned Publishing, 2020
This study examines the role of learned societies as publishers in Finland based on bibliographic information from two Finnish databases. We studied the share of learned societies' peer‐reviewed publication channels (serials with ISSNs and book ...
E. Late   +3 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

“Introduction: ‘Building Partnerships to Transform Scholarly Publishing'” [PDF]

open access: yes, 2014
On February 5th-6th 2014 researchers, students, and other participants gathered together in Whistler, BC, Canada to discuss issues relating to scholarly publishing in Canada.
Aaron Mauro   +2 more
core   +1 more source

Fostering Bibliodiversity in Scholarly Communications: A Call for Action! [PDF]

open access: yes, 2020
Diversity is an important characteristic of any healthy ecosystem, including scholarly communications. Diversity in services and platforms, funding mechanisms, and evaluation measures will allow the scholarly communication system to accommodate the ...
Chan, Leslie   +3 more
core   +2 more sources

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