Results 51 to 60 of about 2,645,731 (390)

Defining tipping points for social-ecological systems scholarship—an interdisciplinary literature review

open access: yes, 2018
The term tipping point has experienced explosive popularity across multiple disciplines over the last decade. Research on social-ecological systems (SES) has contributed to the growth and diversity of the term’s use.
M. Milkoreit   +9 more
semanticscholar   +1 more source

Disaster scholarship [PDF]

open access: yesAdvances in Health Sciences Education, 2021
In this editorial, the Editor considers four domains of disaster in health professions education; the scholarship of disasters, disasters in the conduct of scholarly inquiry, disasters in the presentation of the results of scholarly inquiry, and disasters flowing from the misinterpretation or misappropriation of scholarly activity.
openaire   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Increasing Native Research Leadership Through an Early Career Development Program

open access: yesFrontiers in Public Health, 2022
Inequities impact American Indian, Alaska Native, and Native Hawaiian populations across various health conditions; in particular, many Native communities bear a disproportionate burden of substance use disorder. Such inequities persist despite concerted
Jerreed D. Ivanich   +6 more
doaj   +1 more source

Cultivating Scholarship [PDF]

open access: yes, 2005
Nurturing faculty research and scholarship is a top priority for the law school.
Naismith, Veronica L.
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Imagining Alternatives? Latin American Scholarship on International Economic Law and the Global Economic Order [PDF]

open access: yes, 2020
This Article analyzes the role of Latin American international economic law scholarship within the global economic order.  Many of the problems that Latin Americans face today relate to the global economy, such as labor conditions, access to medicine ...
Perrone, Nicolás M.
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Developing a national undergraduate medical education pain management and substance use disorder curriculum to address the opioid crisis: a program evaluation pilot study

open access: yesBMC Medical Education
Background Pain and addiction are one of the most common reasons for adults to seek health care, yet educational programs focused on pain are often underrepresented in medical school curricula. In January 2021, the Association of Faculties of Medicine of
N. Dalgarno   +7 more
doaj   +1 more source

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