Results 61 to 70 of about 2,645,731 (390)

It is a question of scholarship

open access: yesJournal of the American Dietetic Association, 2003
Scholarship is the opportunity for advanced learning. The new paradigm of scholarship, in addition to research, assimilates teaching, service, and integration scholarships. Many allied health professional organizations reward a variety of scholarly efforts with continuing professional education units (CPEUs).
openaire   +5 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

De-centering and re-centering digital scholarship: A manifesto

open access: yesJournal of New Librarianship, 2017
The continued growth of digital scholarship in librarianship, as evidenced in new positions, new centers, new institutes, new reports/publications, and responding to the ethical turn that our field has undergone in response to current political culture ...
Carolyn Moritz   +6 more
doaj  

Designing, implementing and evaluation of educational program of ethics in education by scenario-based discussion: A Scholarship study

open access: yesJournal of Medical Education and Development, 2021
Introduction: The commitment of faculty members to observe ethical principles and values in the role of a model leads to the strengthening of ethics in students and consequently the development of ethics in society.
Leila sadati   +3 more
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

A critical analysis of the impact of Island Studies Journal: retrospect and prospect [PDF]

open access: yesIsland Studies Journal, 2015
This paper offers a critical review and reflection on the first decade of publishing of scholarly and review articles in Island Studies Journal. Following brief comments on the politics of publishing in any field, and in island studies per se, attention ...
Elaine Stratford
doaj  

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