Results 71 to 80 of about 2,645,731 (390)

Development of a Faculty Learning Community to support Scholarship and Feedback [PDF]

open access: yes, 2018
In an effort to explore the ideas of Scholarship of Learning and Teaching, and to comply with Glasgow’s University’s career development programme, a small group of academics from the College of Medicine, Veterinary and Life Sciences established a ...
Bailey, Emma   +5 more
core  

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

open access: yesFEBS Open Bio, EarlyView.
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper   +5 more
wiley   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock   +8 more
wiley   +1 more source

Keeping the Scholarship in the Scholarship of Teaching and Learning

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2011
As the Scholarship of Teaching and Learning (SoTL) increases in recognition for its contributions to teaching and learning in higher education, it also becomes increasingly important that those wishing to make contributions, and whose area of expertise falls outside of the field of education, make themselves aware of how to conduct educational research.
openaire   +5 more sources

Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons   +8 more
wiley   +1 more source

An ecological approach to understanding transitions and tensions in complex learning contexts

open access: yesnpj Science of Learning
The move away from transmission-based lecturing toward a more student-centred active learning approach is well evidenced in STEM higher education. However, the examination of active learning has generally remained confined to formal timetabled contexts ...
Luke McCrone, Martyn Kingsbury
doaj   +1 more source

Investigating Self-Regulated Learning Differences Based on Gender, Scholarship, and Student’s Housing

open access: yesJurnal Pendidikan Ekonomi dan Bisnis (JPEB), 2020
This study aims to determine the differences students’ self-regulated learning (SRL) based on gender, scholarship, and student’s housing. Referring to Roscoe, our sample of the study is 36 students by using purposive sampling technique..
Nurdian Susilowati   +3 more
doaj   +1 more source

A COMPARISON OF EXTENDED SOURCE-FILTER MODELS FOR MUSICAL SIGNAL RECONSTRUCTION [PDF]

open access: yes, 2014
China Scholarship Council (CSC)/ Queen Mary Joint PhD scholarship; Royal Academy of Engineering Research ...
Cheng, T   +3 more
core  

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