Results 61 to 70 of about 8,413,427 (283)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

The Role of the Principal in Croatian Education: Manager, Leader or Administrator

European Journal of Mental Health, 2014
Manager, Leader or Administrator: The purpose of this study is to examine problems in the fields of educational management and instructional leadership in Croatia that could serve as possible starting points for future studies or research.
Željko Burcar
doaj  

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Administrator Perceptions of School Improvement Policies in a High-Impact Policy Setting

International Journal of Education Policy and Leadership, 2008
This study investigated school administrators’ perceptions of school improvement policies in a high-impact policy environment by measuring the impact of accountability, site-based management, professional development, and scheduling reform on the three ...
MARIO S. TORRES, LUANA ZELLNER, DAVID ERLANDSON   +2 more
doaj   +3 more sources

Administrator Turnover: The Roles of District Support, Safety, Anxiety, and Violence from Students

Behavioral Sciences
Researchers have examined the importance of school administrative support for teacher safety, victimization, anxiety, and retention; however, studies to date have rarely focused on school administrators’ perceptions of support by their district leaders ...
Andrew H. Perry, Linda A. Reddy, Andrew Martinez, Susan D. McMahon, Eric M. Anderman, Ron A. Astor, Dorothy L. Espelage, Frank C. Worrell, Taylor Swenski, Kailyn Bare, Christopher M. Dudek, Jared Hunt, Adriana I. Martinez Calvit, Hyun Ji Lee, Xi Liu   +14 more
doaj   +1 more source

The primary school administrators’ contributions to the organizational socialization of the educational staff and two example cases [PDF]

İnönü Üniversitesi Eğitim Fakültesi Dergisi, 2008
The aim of this study is to determine to which degree school administrators discharge their duties concerning the organizational socialization of teachers and the other staff at schools. The research has been made at a primary school in Ankara. A teacher
Sadık KARTAL
doaj  

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

METAPHORIC PERCEPTION OF PRESERVICE TEACHERS TOWARDS THE CONCEPT OF SCHOOL ADMINISTRATOR

Zeitschrift für die Welt der Türken, 2014
This research aims to reveal the perception of preservice teachers towards the concept of administrator through metaphor. The study group of the research consists of preservice teachers (n=232) studying in the 3rd and 4th grade of the department of ...
Meltem Akın Kösterelioğlu
doaj