Results 181 to 190 of about 16,669,822 (300)

Postoperative Pain Outcomes and Satisfaction in Preschool Versus School-Age Children: A Prospective Multicenter Observational Study. [PDF]

Cureus
El-Tallawy SN, Pergolizzi JV, Alsubaie AT, Hegab MM, Haq AU, Abd El-Rahman AM, Helmy ML, Khan RA, Maghrabi HH, Rasheed AR, Helal DA, Tawfik AM, Elzakaziki SS, Alharbi MM, Mohyeldin AA, Delvi BM.   +15 more
europepmc   +1 more source

PBRM1 Deficiency in Microglia Leads to Excessive Neurogenesis and Autism‐Like Behaviors via the CCL5‐CCR1/5‐β‐catenin Signaling Axis

Advanced Science, EarlyView.
Microglial PBRM1 deficiency drives excessive hippocampal neurogenesis by enhancing CCL5–CCR1/5 signaling, leading to autism‐like behaviors. A pro‐inflammatory IL1α+/TNFα+ microglial subset is identified as a key cellular contributor to this process. PBRM1 represses Ccl5 expression at the transcriptional level.
Yang‐Yang Duan, Lin‐Fei Jiao, Pei‐Pei Liu, Chun‐Hui Duan, Xiao Li, Zi‐Han Zhang, Yue‐Qi Zhang, Xin‐Li Ouyang, Hong‐Zhen Du, Sha Liu, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu   +12 more
wiley   +1 more source

Health of school-age children and adolescents in Saudi Arabia: a systematic review. [PDF]

BMC Public Health
Aljuraiban G, Alsukait RF, Alkanhal N, Hamza MM, Alruwaily A, Rakic S, Cetinkaya V, Herbst CH, Alqunaibet A.   +8 more
europepmc   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

Advanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao, Zhiwei Cheng, Kai Tian, Mengxiong Sun, Zhuoying Wang, Ming Jiao, Jens Luebeck, Kaiyuan Zhu, Xiao Zhang, Dongqing Zuo, Hongsheng Wang, Chongren Wang, Jiakang Shen, Xiaojun Ma, Gangyang Wang, Zongyi Wang, Jing Han, Kaiyuan Liu, Haoran Mu, Weiqi Ma, Yongyong Ren, Shibing Guo, Huangxin Tu, Lingfeng Yu, Yining Tao, Yu Lv, Hui Lu, Owen S. Chapman, Rishaan Kenkre, Lukas Chavez, Zhengdong Cai, Yuqin Yang, Wei Sun, Yafei Jiang, Yingqi Hua   +34 more
wiley   +1 more source

Linking Auditory Brainstem Neural Stability to Parent-Reported Autistic Traits in School-Age Children. [PDF]

Brain Sci
Major DP, Cary E, Matsuba E, Russo N, Prieve B.   +4 more
europepmc   +1 more source

Infection control at school

Schools are environments that provide ideal conditions for the spread of infectious diseases. School-age children are susceptible to many infections. Situations such as students being in close contact for a long time, sharing and using some objects ...
Aksoy, Zahide
core  

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

Advanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang, Yong Xiao, Jiangtao Luo, Xiao Yang, Yayun Yang, Qihang Wu, Chenxin Yu, Zhihao Zhou, Xiaoqing Si, Jiansen Miao, Yiting Tu, Qichen Lu, Boreng Qian, Xiangyang Wang, Jiake Xu, Changcan Shi, Haiming Jin   +16 more
wiley   +1 more source

A 24 month longitudinal cohort study of hookworm infection among school-age children in Ghana: Predictors of persistent and repeated infection. [PDF]

PLoS Negl Trop Dis
Humphries DL, Larbi IA, McLaughlin M, Hu Y, Maldonado L, Otchere J, Quagraine J, Osei-Kwasi HA, Seddoh S, Mensah GE, Osabutey D, Harrison LM, Samani HNL, Koram KA, Wilson MD, Cappello M.   +15 more
europepmc   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Asymptomatic school-age children carry the majority of transmissible Plasmodium falciparum infections. [PDF]

Commun Med (Lond)
Buchwald AG, Vareta J, Nwagbata O, McCann RS, Sixpence A, Matengeni A, Kamzati M, Mangani C, Seydel KB, Wilson ML, Taylor TE, Mathanga DP, Valim C, Laufer MK, Cohee LM.   +14 more
europepmc   +1 more source