Results 41 to 50 of about 6,783,038 (332)

Machines of possibility [PDF]

open access: yes, 2004
In the course of this talk, I want to try and address one main question: what is architecture? Implicit within this are also some reflections on what or who is an architectural historian or commentator?
Borden, Iain
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Development of Standard Designs of Primary School Buildings in Lithuania During the 1920s and 1930s

open access: yesMeno Istorija ir Kritika, 2023
This article analyses the development of standard designs of primary school buildings in Lithuania during the 1920s and 1930s. This process aimed to create simple and comfortable standard school buildings and provide them to the primary schools operating
Vilkončius Evaldas
doaj   +1 more source

How Best to Educate the Next Generation in Historic Preservation [PDF]

open access: yes, 2012
Ten key takeaways from a first-of-its-kind conference on preservation education, hosted by the School of Architecture, Art and Historic ...
Clark, Brian E.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

De la revue d’avant-garde à la reconnaissance publique : la collaboration entre architectes et plasticiens à Liège dans les années 1930

open access: yesIn Situ, 2017
In 1928, students from the Academy of Fine Arts in Liege founded a journal of architecture and town planning called L’Équerre. Although it was something of a latecomer to international avant-garde movements, the monthly magazine set out with a view of ...
Sébastien Charlier
doaj   +1 more source

The Study of the Scale through Space. Teaching Innovation Experience among Architecture Schools: Malaga, Seville and Palermo [PDF]

open access: yes, 2018
The educational innovation project object of this communication focuses on the scale problems that arise in the projects of territorial planning carried out in architecture schools, but also in the loss of the scale concept related to thought and ...
García Bujalance, Susana   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A residence hotel [PDF]

open access: yes, 1901
Thesis (B.S.)--University of Illinois, 1901.Typescript.Bound with: Allen, Albert Miller. An opera house. 1901 -- Hunter, Harry Edgar. A school of architecture. 1901 -- Patrick, Frederick Phillips. A twelve room school building.
Boyd, Edward Parkman
core   +1 more source

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