EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li+15 more
wiley +1 more source
Metabolic Syndrome in School Children
The problem of excessive weight and obesity is increasing world-wide. According to the World Health Organization (WHO), there are over 1.6 billion overweight and 400 million obese people in the world; in 2015, these figures are expected to reach 2.3 billion and 700 million, respectively. Ninety percent of obese adolescents are at risk of becoming obese
openaire +4 more sources
Sex differences shown by 2,544 school children on a group scale of intelligence, with special reference to variability. [PDF]
L. W. Pressey
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This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu+13 more
wiley +1 more source
An Investigation into the Strength of the Skin Capillaries and Indirectly into the Vitamin C Standard of School-Children in the District of Norrbotten, North of the Arctic Circle1 [PDF]
Gunnar Falk+2 more
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Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He+16 more
wiley +1 more source
Detroit's Experience with Undernourished School Children
George T. Palmer
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MENTAL FATIGUE IN DAY SCHOOL CHILDREN, AS MEASURED BY ARITHMETICAL REASONING [PDF]
W. H. Winch
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Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li+16 more
wiley +1 more source
The development of imagination in school children and the relation between ideational types and the retentivity of material appealing to various sense departments. [PDF]
Stephen S. Colvin, Ella Myers
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