Results 161 to 170 of about 11,046,772 (363)

Integrating Single‐Cell Transcriptome‐Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune‐Related Drug Targets for Cancers

Advanced Science, EarlyView.
Inspired by evidence triangulation, a new sensitivity method called MR‐DEG is developed, which uses the differentially expressed gene (DEG) results as additional evidence to minimize pleiotropic effects and strengthen Mendelian randomization (MR) causal estimates. Using dynamic single‐cell expression quantitative trait loci (eQTLs) as an example, it is
Jie Zheng, Qian Yang, Haoyu Liu, Huiling Zhao, Shuangyuan Wang, Yi Liu, Xueyan Wu, Yilan Ding, Hui Ying, Youqiu Ye, Xi Huang, Lei Ye, Ruizhi Zheng, Hong Lin, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yi Duan, Hao Guo, Zhongshang Yuan, Philip Haycock, George Davey Smith, Richard M Martin, Guang Ning, Fang Hu, Weiqing Wang, Tom R. Gaunt, Jieli Lu, Yufang Bi   +29 more
wiley   +1 more source

Enhancing cognitive and social-emotional development through a simple-to-administer mindfulness-based school program for elementary school children: a randomized controlled trial.

Developmental Psychology, 2015
K. Schonert-Reichl, E. Oberle, M. S. Lawlor, D. Abbott, Kimberly C. Thomson, T. Oberlander, A. Diamond   +6 more
semanticscholar   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Community Versus Assimilation: A Study In American Assimilation at Saint Joseph\u27s Indian Industrial School [PDF]

, 1997
No govemment policy has had more of an impact on American Indians than the boarding school movement of the early to mid-twentieth century. This movement isolated American Indian children from their homes and communities and attempted to assimilate them ...
Shillinger, Sarah
core   +1 more source

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

Advanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan, Junqin Chen, Arpit Mishra, Aaron Stewart, Faisal Anees, Ting‐Hsuan Chen, Judith Dominguez, Christine Payne, Michael E. Lipkin, Pei Zhong, Po‐Chun Hsu   +10 more
wiley   +1 more source

Simulating the impacts of cash transfers on poverty and school attendance: The case of Cambodia [PDF]

Using the Cambodia Socioeconomic Survey 2004 and employing micro-static simulation techniques, we measure the potential impacts of cash transfer programs for children to identify targeted groups that will have the most effect on poverty and school ...
Meng, Channarith, Pfau, Wade Donald
core   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

Advanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen, Jinsi Chen, Li Huang, Xingqiang Lai, Kai Xia, Qiying Lu, Bingbing Xie, Yinong Huang, Yuan Qiu, Tao Wang, Jianqi Feng, Yuanjun Guan, Siyao Che, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source

Empirical analysis of school attainment/progression in Cameroon. [PDF]

In Cameroon, only 1/3 of children progress to secondary education. This paper estimates a sequential model of school attainment to investigate the role played by family background and individual characteristics in keeping children at school up to the end
TENIKUE Michel
core   +1 more source

Math in Motion [PDF]

, 2014
Everything we know about the universe rests on the foundation of mathematics. Somehow, though, the magic of mathematics – the true power of numbers and their beautiful wildness – gets lost in math class.
Alcaine, Jose, Barden, Diana, Floyd-Miller, Lori, Grace E. Harris Leadership Institute, Virginia Commonwealth University, MacIver, Blake, Marshall, Lea, Nelson, Angela, Vahdani, Thomas, Witten, Tarynn   +8 more
core   +1 more source

Overweight and Obesity among Primary School Going Children in Urban Agra

, 2021
Iqbal Aqeel Khan, Geetu Singh, Kunver Viresh Singh   +2 more
openalex   +1 more source