Results 101 to 110 of about 12,952,263 (293)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Vanderbilt Law School Death Penalty Debate

open access: yes, 2009
Includes descriptive metadata provided by producer in QuickTime movie file: "Law School - General Events - Vanderbilt Law School Death Penalty Debate - Vanderbilt University > From the Colleges > Law School > General Events > Vanderbilt Law School Death ...
Vanderbilt University. Law School
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Konstruksi Toleransi Siswa dalam Praktik Interaksi Sehari-Hari: Studi Etnografi di SMPK Shining Stars

open access: yesJurnal Humanitas: Katalisator Perubahan dan Inovator Pendidikan
This study aims to analyze how tolerance is constructed through everyday practices at SMPK Shining Star sTimika, a school characterized by multiethnic and multireligious student backgrounds.
Melisa Br Tarigan   +4 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

1909 School of Marine Engineering (poster) [PDF]

open access: yes, 2014
A poster image of showing the the School of Marine Engineering at the Naval Academy in Annapolis in 1909, and the USS Connecticut, flagship of the Great White ...

core   +1 more source

Home - About - Disclaimer - Privacy