Results 81 to 90 of about 12,952,263 (293)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Parent Involvement Through a Practice Theory Lens
Education SciencesThis paper suggests the use of practice theory as a lens for considering the interactions between parents (or those acting as the main support for children) and school staff. Practice theory, arising from separate strains of philosophy, was first used to
Janet Goodall
doaj +1 more source
The effectiveness of Religious and Cultural values in South African Schools: A case study on the effectiveness of Religious and Cultural values in South African Schools Post Apartheid Era [PDF]
E-Journal of Humanities, Arts and Social SciencesThis paper explores the effectiveness of religious and cultural values in South Africa during the post-apartheid era. Currently, South African schools are faced with unrest and instability triggered by social ills such as lawlessness, bullying and ...
Simbongile Gxagxisa, Mlungiseleli Ziduli
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Historic Timeline Root Hall Naval Postgraduate School [video]
, 2009 A collage of images, both historic and contemporary, showing the changes to the historic Naval Postgraduate School site in Monterey, California.
Naval Postgraduate School, Sanders, John
core +2 more sources
Psychological school climate: on the structure of the notion [PDF]
Современная зарубежная психология, 2015 The article regards the structure of the notion "school structure". The traditionally singled out components of school climate — structure and culture — are amended by the notion of an "individual", which becomes central for the concept of school ...
Fedunina N.Y.
doaj
The Catholic School Culture in the Context of Salesian Pedagogy
Paedagogia Christiana, 2016 Man creates culture, but it shapes his life. The symbol of the place of education in culture is the school. The cultural identity of the school usually consists of a few basic elements. It is a multi-layered phenomenon, and the values, norms, beliefs and
Stanisław Chrobak
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Implementasi Pendidikan Karakter di Sekolah Dasar Melalui Penguatan Pelaksanaan Kurikulum
Jurnal Pendidikan dan Kebudayaan, 2010 Nowadays we should be proud because the more Indonesian students have succeeded in International Science Olympic. The Indonesian student team was even once to be overall champion in the International Conference of Young Scientists with participant from ...
Sri Judiani
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source