Results 221 to 230 of about 12,952,263 (293)

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

Patient-derived 3D organotypic co-cultures as a long-term ex vivo model for pleomorphic adenoma of the parotid gland. [PDF]

Sci Rep
Hoch CC, Weiser T, Stögbauer F, Johnson F, Multhoff G, Bashiri Dezfouli A, Wollenberg B.   +6 more
europepmc   +1 more source

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

Advanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko, Chiamaka Akah, Ravinder Dahiya   +2 more
wiley   +1 more source

MiR-125b-5p promotes pemphigus vulgaris pathogenesis by modulating desmosome structures. [PDF]

Biosci Rep
He W, Xiao T, Hua H, Xing Y, Shang P, Fu J, Zheng LW, Wei P.   +7 more
europepmc   +1 more source

Through the Cultural Prism: The Influence of a Distinctive Chinese Personality-Junzi Personality-On Psychosocial Adjustment in China. [PDF]

Int J Psychol
Zhao B, Liu C, Muhetaer P, Hu P.
europepmc   +1 more source

Correction: Preservice teachers' attitudes toward pedagogical humour: the role of physical activity, sociodemographic factors, and academic discipline. [PDF]

BMC Psychol
Çakır Z, Atıkkaş F, Türkmen M, Şengönül A, Yaman MS, Öktem T, Gönen M, Güzel S, Yel K.   +8 more
europepmc   +1 more source

Correction: Editorial: Innovative organoid co-culture systems for enhanced precision medicine in cancer and beyond. [PDF]

Front Med (Lausanne)
Glaser T, Ecker R, Ritter U.
europepmc   +1 more source

Drug development targeting the mitochondrial respiratory chain of Sparganum proliferum: Initial biochemical and drug discovery insights into the enigmatic helminth parasite. [PDF]

PLoS Negl Trop Dis
Enkai S, Nakano Y, Koyanagi M, Arimura Y, Kanuka H, Ishiwata K.   +5 more
europepmc   +1 more source

RUNX1+23 enhancer marks erythro-megakaryocyte lineages in early waves of hematopoiesis in human ESC differentiation. [PDF]

Blood Adv
Nishida C, Kobayashi M, Syed A, Kramer P, Cheng H, Wenzel PL, Osato M, Chobirko JD, Grimson A, Slukvin II, Davis BR, Yoshimoto M.   +11 more
europepmc   +1 more source