Results 91 to 100 of about 6,542,132 (309)

Evaluation of implementation and effect of primary school based intervention to reduce risk factors for obesity [PDF]

open access: yes, 2001
OBJECTIVES: To implement a school based health promotion programme aimed at reducing risk factors for obesity and to evaluate the implementation process and its effect on the school.
Barth, J.H.   +5 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Learning utility of smart school learning space: the impact of spatial factors via visual stated preference method

open access: yesJournal of Asian Architecture and Building Engineering
In the era of Education 4.0, the development of smart schools represents a significant step forward. Learning spaces are critical to the success of smart school construction in primary and secondary schools, due to their significant impact on school-age ...
Yu Zhang   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Perspectives in High-Energy Physics [PDF]

open access: yes, 2000
I sketch some pressing questions in several active areas of particle physics and outline the challenges they present for the design and operation of detectors.Comment: 27 pages, 12 figures, uses aipproc (included) and boxedeps.
Quigg, Chris
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Bridging the Gap [PDF]

open access: yes, 2016
School districts across the country are increasingly seeking out digital tools to support the work of educators, in the hopes of improving students' academic achievement. With the rapid emergence of this new market, many districts have been challenged by
Adriana Villavicencio   +2 more
core  

Designing Effective Simulation Games for Active Learning in Systems Engineering [PDF]

open access: yes, 2019
Simulation games have been an effective method of teaching, especially for Systems Engineering concepts. The hands-on activities facilitate active, experiential, and collaborative learning with fun elements.
Gupta, Nihar, Wan, Hung-da
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Aspirations and the design of vertical schools

open access: yesDiscover Education
In Australia, urban vertical schools are relatively new and invite new aspirations for education. Aspirations are often represented in educational leadership literature and architecture in terms of a shared vision guiding decisions and creating alignment
Linda Carroli, Jill Willis, Jill Franz
doaj   +1 more source

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