Results 91 to 100 of about 6,542,132 (309)
Evaluation of implementation and effect of primary school based intervention to reduce risk factors for obesity [PDF]
OBJECTIVES: To implement a school based health promotion programme aimed at reducing risk factors for obesity and to evaluate the implementation process and its effect on the school.
Barth, J.H. +5 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In the era of Education 4.0, the development of smart schools represents a significant step forward. Learning spaces are critical to the success of smart school construction in primary and secondary schools, due to their significant impact on school-age ...
Yu Zhang +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Perspectives in High-Energy Physics [PDF]
I sketch some pressing questions in several active areas of particle physics and outline the challenges they present for the design and operation of detectors.Comment: 27 pages, 12 figures, uses aipproc (included) and boxedeps.
Quigg, Chris
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
School districts across the country are increasingly seeking out digital tools to support the work of educators, in the hopes of improving students' academic achievement. With the rapid emergence of this new market, many districts have been challenged by
Adriana Villavicencio +2 more
core
Designing Effective Simulation Games for Active Learning in Systems Engineering [PDF]
Simulation games have been an effective method of teaching, especially for Systems Engineering concepts. The hands-on activities facilitate active, experiential, and collaborative learning with fun elements.
Gupta, Nihar, Wan, Hung-da
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Aspirations and the design of vertical schools
In Australia, urban vertical schools are relatively new and invite new aspirations for education. Aspirations are often represented in educational leadership literature and architecture in terms of a shared vision guiding decisions and creating alignment
Linda Carroli, Jill Willis, Jill Franz
doaj +1 more source

