Results 101 to 110 of about 6,542,132 (309)
Design of Sekolah Penggerak principal leadership in implementing best practices
JPPI (Jurnal Penelitian Pendidikan Indonesia)This research aims to determine the leadership design of Sekolah Penggerak principals in instilling good practices in high schools in East OKU Regency. The method used in this research is research and development.
Sutarjo Sutarjo +2 more
doaj +1 more source
Sickle cell disease status among school adolescents and their tribal community in South Gujarat [PDF]
, 2009 Objectives: to create awareness, to screen samples of school adolescents and then to reach their community through them by doing surveillance for sickle cell disease. Design: Field based cross-sectional study. Settings: St Xavier`s high school and Vanraj
Chudasama, Rajesh K +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Global Design. Schools in Portugal
Docomomo Journal, 2012 Since its very beginning, the design of educational spaces is strongly connected with issues on pedagogy, hygiene, order and discipline, collective identity (hence with history, traditions, modernity and innovation). To materialize the concept of global design, seeking formal coherence and a close functional and ideological articulation between all ...
openaire +3 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Scientific ReportsThe rapid development of immersive technologies has transformed the tourism experience, enabling tourists to explore destinations virtually before physical visits.
Li Chen +5 more
doaj +1 more source
Structures of policy : Building Bulletin in Postwar Britain [PDF]
, 2016 School design in Great Britain underwent great typological change in the post-war era, necessitated by depleted construction labour and materials, coupled with a bourgeoning school-age population resulting from the population boom and an expanded student
Lang, Ruth
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source