Results 111 to 120 of about 3,120,187 (310)
Exploring differential science performance in Korea and South Africa: A multilevel analysis
Perspectives in Education, 2014 This paper reports on secondary analysis of TIMSS 2003 data with the aim of explaining the difference in science achievement of Korean and South African learners. The question asked by this research, i.e.
Mee-Ok Cho +2 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Strengthening School Effectiveness Through Collaborative Working : An Evaluation of Training Impact
Jurnal PaedagogyThis study aims to examine the effectiveness of experiential learning-based collaborative working training in enhancing the collaborative competence of stakeholders in elementary school setting.
Yushi Widya Pramita, Tjut Rifameutia
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
School Accountability and Administrator Incentives in California [PDF]
, 2009 Examines the impact of the No Child Left Behind Act's incentives for principals, superintendents, and school boards on accountability. Calls for transparency on the effectiveness of schools, districts, and interventions in improving student ...
S. Eric Larsen
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Shizi Peiyu Yu Jiaoshi Zhuanye Fazhan Qikan, 2008 本研究旨在探討知識管理與學校效能的重要內涵與構面；並瞭解國中兼任行政職務教師的知識管理對學校效能之影響，以作為提昇學校效能之參考。本研究以台中市之公立國民中學教師兼任行政職務301 人為對象，採問卷調查方式，其研究結果如下：（一）知識管理可以分為知識的取得、知識的儲存、知識的應用、知識的分 享、知識的創新5 個構面，及25 個指標。（二）學校效能可以分為學生學習表現、教師教學品質、行政績效表現、校園環境設備、社區家長支持5 個構面，及25 個指標。（三）國中兼任行政職務教師需具備充分的知識管理能力 ...
陳聰文 Chen, Tsong-Wen +2 more
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