Results 131 to 140 of about 3,082,840 (310)
School Effectiveness Framework pilots: an evaluation (research document) [PDF]
"This report looks at the pilot to introduce the School Effectiveness Framework in schools in Wales. The School Effectiveness Framework (SEF) is an ambitious Welsh Assembly Government (WAG) programme that aims to raise attainment, to close the gap in ...
Holtom, Duncan, Lloyd-Jones, Sarah
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Infrastructure Choices in Education: Location, Build or Repair [PDF]
The purpose of this study is to develop a model to arrive at a joint optimizing strategy for the use of a given capital budget for the construction of new school buildings and for the repair of the already existing schools.
Andrey Klevchuk +2 more
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A Review of Disciplinary Interventions in K12 Public Education [PDF]
As a part of the Achieving Racial Equity in School Disciplinary Policies and Practices study from the Metropolitan Educational Research Consortium, this literature brief offers an overview of school discipline interventions in K12 public education.
Coffee, Mariah +3 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The effectiveness of English secondary schools for pupils of different ability levels [PDF]
'League table' information on school effectiveness in England generally relies on either a comparison of the average outcomes of pupils by school, e.g. mean exam scores, or on estimates of the average value added by each school.
Anna Vignoles +2 more
core +3 more sources
Public spending on education: Its impact on students skipping classes and completing school [PDF]
Empirical results using cross-country data suggest that public spending on education increases the rate of students skipping school but does not influence the rate of students completing school.
Yamamura, Eiji
core +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Your PEL questionnaire development - evaluation of the impact of health education programs in schools. [PDF]
Artigo apresentado em Coimbra no âmbito do Anuual Meeting 2019 da Escola Superior de Tecnologia da SaúdeThe Your PEL project emerged in response to requests from regional school groups and community care units that have identified the need to assess the ...
Amendoeira, José +9 more
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Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

