Results 21 to 30 of about 1,711,238 (314)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Impact of daily, oral pre-exposure prophylaxis on the risk of bacterial sexually transmitted infections among cisgender women: a systematic review and narrative synthesis [version 2; peer review: 2 approved]

Wellcome Open Research, 2022
Background: There are concerns that the use of pre-exposure prophylaxis (PrEP) may result in an increased incidence of sexually transmitted infections (STIs).
Helen Ward, Erica Crittendon, Vasiliki Papageorgiou, Bethan Davies, Flavien Coukan   +4 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Learning from experience: the case study of a primary school [PDF]

, 2012
This thesis is a case study about learning from experience in a primary school. The enquiry applies a psychoanalytic idea in an educational context. The focus arose from Bion’s idea: ‘Container-contained’ (Bion, 1962) which proposes that the capacity to ...
Ashford, E.
core  

“Best Days of Our Lives?” Exploring the School Experiences of Women with ADHD Based on Diagnosis During or After School

Disabilities
Attention Deficit Hyperactivity Disorder (ADHD) is a neuro-behavioural condition associated with limitations and deficits. Previous literature has largely focused on the lived experiences of males with ADHD.
Sorcha Walsh, Vlad Glaveanu
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Girls who learn to serve: aAn ethnography exploring the gendered experience of school-based volunteering [PDF]

, 2021
This is a study of a school-based volunteering programme; an ethnography of six girls enrolled into the Duke of Edinburgh (DofE) scheme at their secondary school in a deprived coastal community in the South-East of England.
Lau, E.
core  

Doing community involvement care-fully: using an ethic of care to guide involvement in research on women’s health after pregnancy complications and loss

Research Involvement and Engagement
Consumer and Community Involvement (CCI) occurs when people with lived experience collaborate with researchers to design and conduct research. CCI has widely accepted benefits and is increasingly expected by funders and publishers.
Bec Jenkinson, Melanie McKenzie, Ayme Limmer, Valerie Charlton, Leah Hardiman, Anna Lee Ura, Sheleigh Lawler, Carissa Bonner, Jenny Doust   +8 more
doaj   +1 more source

Building an institutional AI Learning Tutor: A case study on supporting flipped classroom in a business school

Ubiquity Proceedings
This experience presents the design, implementation, and evaluation of an institutional AI Learning Tutor to support undergraduate students' learning within a flipped classroom approach in business school settings.
Irina Otmanine, Denys Giordano, Frederic Munier   +2 more
doaj   +1 more source