Results 121 to 130 of about 17,211,696 (413)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Relações entre violência doméstica e agressividade na adolescência

open access: yesCadernos de Saúde Pública
Este é um estudo exploratório sobre violência doméstica realizado na cidade de Porto Alegre, com alunos de duas escolas: uma pública e outra particular.
Stela Nazareth Meneghel   +2 more
doaj  

Situational analysis on safety and health in primary school in Kota Bharu [PDF]

open access: yes, 2009
Background : Safety and health is one of major concerns in public health issues. There are lots of injuries or accidents reported in the news which include school accidents and injuries.
Nurul AH,, Tengku MA,
core  

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

Prevalência de fluorose dentária em escolares de Marinópolis, São Paulo

open access: yesCadernos de Saúde Pública
O objetivo deste estudo foi determinar a freqüência e severidade da fluorose dentária em escolares de 5 a 12 e de 15 anos de idade da cidade de Marinópolis, São Paulo, Brasil, com o propósito de se obter um banco de dados-base inicial para o ...
Ioneide Maria Gomes Brandão   +3 more
doaj  

Predicting Adolescents’ Leisure-Time Physical Activity Levels: A Three-Wave Prospective Test of the Integrated Model of Self-Determination Theory and the Theory of Planned Behavior

open access: yesBehavioral Sciences
A three-wave prospective study was conducted to provide a better understanding of the ability of the integrated model of self-determination theory (SDT) and the theory of planned behavior (TPB) to predict future physical activity (PA) engagement among ...
Diana L. Y. Su   +4 more
doaj   +1 more source

Intervención educativa con docentes: fortalecimiento de habilidades psicosociales para la vida y hábitos saludables con escolares en Bogotá / An educational intervention with teachers: strengthening the psychosocial life skills and healthy habits of school students in Bogotá

open access: yesRevista Facultad Nacional de Salud Pública, 2015
Resumen Objetivo: Determinar los resultados de la intervención educativa dirigida a docentes para el fortalecimiento de hábitos saludables y habilidades psicosociales para la vida en niños y niñas de básica primaria en instituciones públicas de la ...
Blanca P. Mantilla-Uribe   +3 more
doaj   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

open access: yesMolecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

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