Results 131 to 140 of about 17,553,900 (366)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
There has been increasing interest in using of web-based surveys—rather than paper based surveys--for collecting data on alcohol and other drug use in middle and high schools in the US.
Shobana Raghupathy, Stephen Hahn-Smith
doaj
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Establishing a whole school food policy [PDF]
This resource was originally developed and produced by the Health Promotion Agency for Northern Ireland as part of the School food: top marks programme.
core
Background/Objectives: On 6 June 2023, two varicella cases were reported at a highly vaccinated elementary school in Gyeonggi Province, Republic of Korea. We investigated the outbreak to describe its transmission dynamics; quantify attack rates in school,
Gipyo Sung, Jieun Jang, Kwan Lee
doaj +1 more source
Oxford Child Health Survey : Stature and Skeletal Maturation in the Pre-School Child [PDF]
RoyM. Acheson, David Hewitt
openalex +1 more source
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Medical and Veterinary Entomology: A Textbook for use in Schools and Colleges, as well as a Handbook for the use of Physicians, Veterinarians and Public Health Officials [PDF]
L. O. Howard
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source

