Results 131 to 140 of about 16,910,144 (412)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Understanding the Facilitators and Barriers to COVID-19 Vaccine Uptake Among Teachers in the Sagnarigu Municipality of Northern Ghana: A Cross-Sectional Study

Risk Management and Healthcare Policy, 2022
Stephen Dajaan Dubik Department of Public Health, Catholic University College of Ghana, Fiapre, GhanaCorrespondence: Stephen Dajaan Dubik, Email stephendubik@gmail.comPurpose: This research aims to identify facilitators and barriers to COVID-19 ...
Dubik SD
doaj  

Chapter 2 School Health Services [PDF]

, 1953

openalex   +1 more source

Analysis of Selected Physical Fitness, Physiological, and Psychological Variables among Government, Government-Aided, and Private School Boys in Chennai District

International Journal of Innovative Science and Research Technology
Purpose: This study aims to analyze and compare selected physical fitness, physiological, and psychological variables among boys from government, government- aided, and private schools in the Chennai district.
A. U. Parvathi, Sanjith. Tk
semanticscholar   +1 more source

Adolescent Mental Health Literacy: Young People\u27s Knowledge of Depression and Social Anxiety Disorder [PDF]

, 2016
Scott Greenspan outlines a brief overview of the introduction, methods, results, and implications of this study focusing on the level of knowledge young people have on mental health.
Greenspan, Scott
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Caries Incidence in School-Based Prevention Programs in the Presence of Interval Censoring

Children
Background/Objectives: School-based caries prevention can increase access to critical dental services and reduce oral health inequities. However, little is known regarding the incidence of dental caries in children participating in school caries ...
Ryan Richard Ruff
doaj   +1 more source

School Hygiene: The Laws of Health in Relation to School Life [PDF]

, 1887
Arthur Newsholme
openalex   +1 more source