Results 51 to 60 of about 3,822,591 (268)

Duração do sono em adolescentes de diferentes níveis socioeconômicos Sleep duration in adolescents of different socioeconomic status

open access: yesJornal Brasileiro de Psiquiatria, 2009
OBJETIVO: Investigar a duração de sono na adolescência em diferentes níveis socioeconômicos. MÉTODO: Foram investigados 863 adolescentes de 10 a 19 anos em duas escolas de São Paulo, SP, Brasil.
Maria Perpeto Socorro Leite Bernardo   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Are our rural adolescents eating healthy?: Implications for redesigning school health interventions – A cross sectional study in rural Coimbatore

open access: yesIndian Journal of Public Health, 2019
Background: Adolescence is a period of transition where independence in thinking and behavior is established and food choices that are made are followed for several years, and this can influence their health in adulthood.
Subhashini Ganesan   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A concepção sobre saúde do escolar entre professores do ensino fundamental (1ª a 4ª séries) The concept of student health as viewed by early elementary school teachers (1st- 4th grades)

open access: yesHistória, Ciências, Saúde: Manguinhos, 2005
O presente estudo investiga a concepção sobre a saúde do escolar entre os docentes do ensino fundamental e caracteriza a formação desses profissionais nessa temática. Utilizou-se metodologia qualitativa, numa amostra constituída por 45 professores.
Marcos Henrique Fernandes   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Assessing Teacher Satisfaction with the SistaUKS System: A New Approach to School Health Program Stratification [PDF]

open access: yesJournal of Health Sciences and Surveillance System
Background: The School Health Program (UKS) is assessed to enhance its effectiveness in improving students’ health levels. SistaUKS, a health information system comprising software and data, facilitates the automation of the UKS stratification assessment
Ayu Khoirotul Umaroh   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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