Results 101 to 110 of about 274,012 (313)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

An Analysis of Urban School Leaders' Role in Community Support and Involvement

open access: yesSchool Leadership Review, 2017
While school systems have the arduous task of educating a plethora of diverse students from different backgrounds and social economic status, the task is multifaceted.
Mary Keller Boudreaux
doaj  

School Leadership [PDF]

open access: yesProceedings of ‏The 3rd International Conference on Teaching, Learning and Education, 2021
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Texas School District Liability in Pupil Transportation: A Legal Analysis of the Texas Tort Claims Act and Sovereign Immunity

open access: yesSchool Leadership Review, 2016
Despite information and research being available in the area of tort liability, including relevant topics in public school law, there are limited resources on the topic for school transportation litigation.
Kayne M. Smith   +3 more
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Predictive models for school leadership and practices [PDF]

open access: yes, 2019
Description A successful administrator is one who applies suitable or appropriate leadership styles in various situations or contexts. It is crucial to investigate how effective administrators lead their organizations in challenging and difficult ...

core  

Supporting New School Leaders Through Mentoring

open access: yesSchool Leadership Review, 2019
Mentoring may best be defined as “a process where one person provides individual support and challenge to another professional (Bush, 2009, p.379). The importance of mentoring new teachers and administrators has long been recognized.
Lisa A. Bertrand   +2 more
doaj  

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