Results 31 to 40 of about 1,813,642 (313)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Entrepreneurial leadership practices and school innovativeness
South African Journal of Education, 2014 Entrepreneurial leadership, as a distinctive type of leadership required for dealing with challenges and crises of current organizational settings, has increasingly been applied to improve school performance.
Zaidatol Akmaliah Lope Pihie +2 more
doaj
, 2021 This paper examines the differing practices for leadership and management in schools.
States, Jack +2 more
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Distributed Leadership:Still in the gift of the headteacher [PDF]
, 2013 Contemporary efforts to reconceptualise the teaching profession in Scotland as seen with the Donaldson (2011) "Review of Teacher Education," the McCormac (2011) "Review of Teacher Employment" and the GTCS (2012) "Review of Professional Standards" are ...
Torrance, Deirdre
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Costs of Participation in the School Administration Manager (SAM) Process [PDF]
, 2011 Analyzes variations in school districts' implementation costs, by model, of the school administration manager process to help principals increase the time they spend on instructional leadership.
Brenda J. Turnbull, M. Bruce Haslam
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Educational Leadership in Haiti: A Case Study of Innovative and Exemplary Leadership in a Fragile State [PDF]
, 2004 In this study, we consider three school leaders in Haiti who provide examples of innovative and exemplary leadership practices in the midst of challenging circumstances. Using a framework of innovative (Moolenaar, Daly, & Sleeger, 2010; Rogers, 2003) and
Arabaci, M +3 more
core +2 more sources
Reflections of Practicing School Principals on Ethical Leadership and Decision-Making: Confronting Social Injustice [PDF]
, 2015 The study objective was to identify leadership dilemmas of practicing school administrators and their own codes of ethics to inform understandings of ethical decision-making. Ethical decision-making underpins leadership practice, theory, and preparation.
Gardiner, Mary E., Tenuto, Penny L.
core +1 more source